United Therapeutics Corporation

Senior Scientist - Enhanced Lung

United Therapeutics Corporation$127K — $170K *
Pharmaceuticals & Biotech
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • Master’s Degree in molecular biology, gene therapy, virology, biomedical engineering, or related field
  • 8+ years of biotech/pharma experience with a Master's or 5+ years with a PhD
  • Experience with viral vector systems (AAV, LVV, AdV)
  • Strong data analysis and experimental design skills
  • Ability to mentor and motivate team members

Responsibilities

  • Plan and oversee gene delivery strategies in lung tissue models
  • Optimize transduction efficiency and safety profiles
  • Support preclinical large-animal studies and data analysis
  • Develop and validate molecular and functional assays
  • Collaborate cross-functionally with various teams
  • Contribute to IND-enabling studies and regulatory documentation
  • Mentor junior scientists and research associates

Benefits

  • Comprehensive medical/dental/vision/prescription coverage
  • Employee wellness resources
  • Savings plans (401k and ESPP)
  • Paid time off and paid parental leave
  • Disability benefits
Full Job Description

California, US residentsclick here.

The job details are as follows:

The Enhanced Lung Program focuses on developing novel technologies to enhance donor lung performance and improve transplant outcomes. Our scientists work at the intersection of organ perfusion, gene therapy, and bioengineering to modify and optimize lungs outside the body prior to transplantation.

Who you are

This is science you can feel proud of. As a Senior Scientist on our Enhanced Lung program, you’ll be hands‑on driving gene modification strategies that move engineered and donor lungs closer to real clinical impact. This role is about designing smart experiments, running them with purpose, and translating results that matter—across EVLP systems, vector delivery, and functional validation. You’ll collaborate deeply across disciplines, mentor growing scientists, and play a critical role in bringing bold ideas into execution. If you thrive on ownership, love solving complex biological problems, and want your work to meaningfully advance patient care, this is the kind of role where your science truly counts.

The Senior Scientist will play an important technical role in advancing gene modification strategies for ex vivo lung perfusion (EVLP) and enhanced lung development. This individual will design, execute, and interpret studies focused on vector delivery, gene editing, transduction optimization, and translational functional validation within engineered or donor lungs. The role requires strong hands-on expertise in gene therapy or a closely related field and the ability to operate within a cross-functional translational team.

  • Plan and oversee gene delivery strategies (AAV, lentiviral, adenoviral, mRNA/LNP, or other platforms) in lung tissue models and EVLP systems
  • Optimize transduction efficiency, durability of expression, and safety profiles
  • Support preclinical large-animal studies, including experimental design and data analysis
  • Develop and validate molecular and functional assays (qPCR, ddPCR, ELISA, flow cytometry, multiplex assays, etc.)
  • Collaborate cross-functionally with device, manufacturing, analytical, and regulatory teams
  • Contribute to IND-enabling studies and regulatory documentation
  • Mentor junior scientists and research associates
  • Contribute to publications and patent submissions, protocols, abstracts, posters, etc. and other publication development
  • Present data internally and externally
  • Assist with EVLP

Minimum Requirements

  • Master’s Degree in molecular biology, gene therapy, virology, biomedical engineering, or related field
  • 8+ years of related biotech/pharma industry experience with a Master's Degree or 5+ years of related biotech/pharma industry experience with a PhD
  • Experience with viral vector systems (AAV, LVV, AdV) or non-viral gene delivery platforms
  • Strong data analysis and experimental design skills
  • Demonstrated ability to work in a fast-paced translational environment
  • Good written and oral communication skills
  • Ability to work independently and in multidisciplinary teams
  • Strong analytical skills
  • Ability to mentor and motivate team members
  • Highly self-motivated
  • Ability to organize and present data

Preferred Qualifications

  • Doctor of Philosophy (PhD) in molecular biology, gene therapy, virology, biomedical engineering, or related field
  • Experience with lung biology, transplant models, or EVLP
  • Industry experience
  • Experience working with human tissue

The salary range for this position is $127,500 - $170,000 per year and reflects our good-faith estimate of the compensation for this role at the time of posting. An employee’s position within the salary range will be based on factors such as education, qualifications, experience, skills, geographic location, and business needs, as well as other factors permitted by law at the time of posting. This range may be modified in the future based on company and market factors.

Job Location

This role is based at our Silver Spring, MD location.

Eligible employees may participate in the Company’s comprehensive benefits suite of programs, including medical / dental / vision / prescription coverage, employee wellness resources, savings plans (401k and ESPP), paid time off & paid parental leave benefits, disability benefits, and more. For additional information on Company benefits, please visit

About United Therapeutics Corporation

United Therapeutics Corporation is a biotechnology company that develops and commercializes innovative products to address the unmet medical needs of patients with chronic and life-threatening diseases. The company was founded in 1996 and is headquartered in Silver Spring, Maryland. United Therapeutics has a portfolio of products that includes treatments for pulmonary arterial hypertension, neuroblastoma, and other diseases. The company's mission is to improve the lives of patients by developing and commercializing innovative therapies. United Therapeutics has received numerous awards for its contributions to the biotechnology industry.
Learn more about United Therapeutics Corporation
Size
965 employees
Market Cap
$12.4 billion
Industry
Net Income
$514.8 million
5 Year Trend
+1.1%
Revenue
$1.4 billion
NASDAQ

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