At Roche, we are developing the next-generation of sequencing systems. By accelerating clinical research, streamlining workflows, and expanding assay menus, we are also broadening access to genomic data and lowering barriers to adoption. From robust sample isolation and preparation tools to novel sequencing technology and advanced bioinformatics, we are developing differentiated, highly integrated end-to-end solutions for next-generation sequencing workflows.

Our Systems Technology Group, a part of Roche Sequencing Solutions, is focused on creating and advancing technologies to significantly enhance DNA sequencing workflows. We are seeking a Senior Research Engineer to contribute to the design, development, characterization, and integration of cutting-edge sequencing systems. This is a hands-on role focused on solving the fluidic and consumable challenges at the heart of our next-generation platforms. We are looking for someone who exhibits a high degree of motivation, independence, and resourcefulness to help us develop solutions to our automation challenges in a fast-paced and collaborative environment.

The Opportunity

• You will contribute to the research and early development of specialized consumables and related hardware for next-generation sequencing systems..

• You will design, fabricate, assemble, characterize, troubleshoot and optimize custom devices, consumables, test fixtures and breadboards.

• You will evaluate different concepts and design paths to assess feasibility. Collect and present data and findings to the team and participate in or drive down-selection efforts.

• You will create and maintain comprehensive design documentation for your sub-systems, including requirements, schematics, diagrams, CAD models, manufacturing drawings, and material specifications.

• You will contribute to the acquisition, installation, bring-up, utilization and maintenance of new tools and equipment for use in the fabrication or testing of devices and consumables
  

Who You Are:
(Required)

• You have a Bachelor's in Mechanical Engineering (or a closely related discipline), with 4+ years of relevant industry experience; or a Master's in Mechanical Engineering (or a closely related discipline), with 2+ years of relevant industry experience; or a PhD in in Mechanical Engineering (or a closely related discipline), with 1+ years of relevant industry experience.

• You have 3+ years working with various fluidic devices

• You have demonstrated hands-on experience characterizing and testing complex fluidic systems and consumable interfaces for life science or diagnostic instrumentation.

• You have experience in experimental design for fluidic characterization and the use of Python for device control, automated test bench execution, and data acquisition/analysis.

• You have a demonstrated level of proficiency with machine shop tools, measurement equipment, and rapid prototyping technologies.

• You have a demonstrated level of troubleshooting skills, with a solid understanding of physics, chemistry and engineering fundamentals.

• You have experience working with deadlines, in a collaborative setting and a high level of scientific curiosity.
  

Preferred Qualifications:

• You have an advanced degree in Mechanical Engineering

• You have experience using fluidic diagramming tools and CFD or FEA tools to guide fluidic and thermal design decisions.

• You have experience with DNA sequencing, DNA synthesizers and other complex fluidic automation instrumentation

• You have experience working with scientists and chemists to solve multi-disciplinary problems.

• You have experience with advanced microfabrication techniques, including lithography, thin-film deposition and wet etching of metals and inorganic materials.

• You have experience in SolidWorks for detailed part and assembly design and the creation of manufacturing drawings.

This is an on-site position based in Santa Clara, CA. (This is not a hybrid position.)

Relocation benefits are not being offered for this role.

The expected salary range for this position based on the primary location Santa Clara, CA is $87,500 - $162,500. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance.

This position also qualifies for the benefits detailed at the link provided below.