Job Description

Title: Senior Manager, Ontology
Location: Cambridge, MA (Hybrid)

About the role:

As a Senior Manager, Ontology, you will be a hands-on R&D BioPharm data curator responsible for harmonizing Research, Development, and Global Medical data into standardized, analysis-ready, FAIR-aligned datasets. You will partner up with data owners/stewards and data platform teams to operationalize metadata standards, ontology/terminology mapping, versioning, and QC-improving throughput through scalable processes and targeted automation.

How will you contribute:

• Curate and harmonize biomedical datasets; ensure completeness, consistency, traceability, and audit readiness using ontology tools and tabular workflows.
• Partner with data owners/stewards to collect required artifacts and build metadata using templates and tooling.
• Map entities to controlled vocabularies/ontologies; manage terminology decisions, documentation, and versioning.
• Maintain application and domain ontologies across environments; follow data exchange processes and define contextual rules to support orchestration, discoverability and reuse.
• Define and execute QC/QA standards, SOPs, and governance practices; produce QC outputs and release documentation.
• Lead cross-functional delivery and stakeholder communication: curation decisions, risks, and tradeoffs.
• Identify and implement workflow improvements, including automation, and contribute to onboarding and best practices for the ontology tool suite.
• Facilitate working sessions and training with stewards/SMEs to resolve definition conflicts and mapping edge cases.

What you bring to Takeda:

• Bachelor's degree with relevant experience or advanced degree (MS/PhD) in life sciences, bioinformatics, data science, or related field.
• 4-7+ years in biomedical data curation/harmonization, data management/modeling, and/or data governance (pharma/biotech/CRO/vendor).
• Experience mapping to controlled vocabularies/ontologies (e.g., NCIT, MedDRA, BAO, CL, CHEBI, Allotrope, PROCO or similar).
• Experience with ontology management tools (e.g., SciBite CENtree, TopBraid Composer, or equivalent).
• Experience defining/executing QC/QA checks and maintaining SOPs.
• Version control experience; ability to track and merge ontology changes.

Preferred qualifications

• Experience partnering with data platform/engineering teams to implement validation/QC/ingestion workflows.
• Familiarity with W3C semantic web/ontology standards (RDF/RDFS/OWL/SKOS/SHACL).

Takeda Compensation and Benefits Summary

We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location:
Boston, MA

U.S. Base Salary Range:
$137,000.00 - $215,270.00

The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and/or from which they will be performing the job. The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. based employees may be eligible for short-term and/ or long-term incentives. U.S. based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S. based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.

Locations
Boston, MA

Worker Type
Employee

Worker Sub-Type
Regular

Time Type
Full time

Job Exempt
Yes