McKesson

Senior Infrastructure Engineer

McKesson$99K — $132K *
Information Technology
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • 8+ years of hands-on experience in enterprise infrastructure or systems engineering roles supporting large-scale, critical environments.
  • Bachelor's degree in Computer Science, Computer Engineering, or related field, or equivalent experience.
  • Expertise in enterprise operating systems, Microsoft Azure, and VMware.
  • Proven track record of executing large-scale server and workload migrations.
  • Advanced proficiency in PowerShell scripting for automation tasks.

Responsibilities

  • Plan, design, and implement migration initiatives for on-premises and cloud environments.
  • Architect scalable and secure infrastructure solutions.
  • Lead large-scale server and data center migrations to Azure and hybrid environments.
  • Leverage Infrastructure as Code tools like Terraform or Ansible for environment management.
  • Ensure compliance with organizational cybersecurity and operational policies.
  • Collaborate with various teams for operational integrity and readiness.
  • Provide post-migration support and troubleshooting for complex infrastructure issues.

Benefits

  • Comprehensive health benefits package.
  • Opportunities for performance-based bonuses and long-term incentives.
  • Access to professional development resources.
  • Flexible working arrangements to promote work-life balance.
  • Employee assistance programs for personal and professional support.
Full Job Description
The Senior Infrastructure Engineer is responsible for planning, designing, and executing enterprise infrastructure modernization initiatives, including large-scale migrations from legacy on-premises environments to Azure Local and hybrid Azure cloud platforms. This role works in close partnership with engineering, architecture, application, operations, and cybersecurity teams to deliver secure, scalable, and resilient infrastructure solutions.

The ideal candidate brings deep hands-on technical expertise across VMware, Microsoft Azure, Azure Local, core server platforms, and automation, with a proven track record of delivering complex data center and enterprise migrations that achieve measurable improvements in performance, reliability, scalability, and cost optimization.

This role requires strong engineering judgment, the ability to execute technically complex work end-to-end, and comfort operating in highly regulated, large-scale enterprise environments.

The Senior Infrastructure Engineer plays a critical role in modernizing McKesson's infrastructure, accelerating cloud adoption, improving platform reliability, reducing technical debt, and delivering tangible business value across the organization.

Infrastructure Strategy & Design:
  • Plan, design, and implement migration initiatives across on-premises, hybrid, and Azure cloud environments.
  • Architect scalable, resilient, and secure infrastructure solutions aligned with McKesson enterprise standards.
  • Evaluate legacy infrastructure and define modernization and migration strategies that support business objectives.


Migration Execution & Delivery:
  • Deliver migration plans that achieve documented performance improvements, availability enhancements, or cost savings.
  • Lead the planning and execution of large-scale server and data center migrations to Azure Local and hybrid cloud environments, ensuring stability, performance, and minimal operational disruption.
  • Partner with application teams to align infrastructure migrations with application architecture and deployment processes.


Automation, Governance & Operational Excellence:
  • Leverage Infrastructure as Code (IaC) tools with Terraform or Ansible to deliver scalable, repeatable, and governance-aligned compute environments that support enterprise reliability and compliance.
  • Maintain accurate and up-to-date system documentation across on-premises, hybrid, and cloud platforms, including the creation, maintenance, and retirement (purging) of Configuration Management Database (CMDB) records, ensuring infrastructure assets, configuration items, and dependencies are properly documented to support operational integrity, lifecycle management, and audit readiness.
  • Utilize and adhere to the McKesson Change Management process to plan, review, and implement changes within production and disaster recovery environments, ensuring minimal disruption and controlled risk.
  • Participate in change reviews, implementation planning, and post-implementation validation to confirm changes meet technical, operational, and business requirements.


Operational Readiness & Cross-Team Collaboration:
  • Ensure infrastructure solutions comply with McKesson cybersecurity, compliance, and operational policies.
  • Collaborate with compute, network, storage, operations, and cybersecurity teams to ensure end-to-end solution integrity and operational readiness.
  • Act as a post-migration escalation point for complex infrastructure issues, providing root cause analysis and remediation, while serving as a trusted technical advisor who clearly communicates recommendations, outcomes, and risks to both technical and non-technical stakeholders.


Section B - General Responsibilities
  • Seek to provide candid and timely feedback to improve performance; openly share information; foster teamwork and innovation by involving team members in problem-solving, decision-making, and creative thinking.
  • Ensure that requirements to internal and external customers are met in a timely and cost-effective manner; solicit feedback from customers to identify opportunities to improve products and/or services; resolve minor conflicts and involve team members in problem resolution.
  • Apply decision-making authority and autonomy needed to deliver accountabilities of job/role; seek approval from others on matters outside of job/role scope; when required, make decisions regarding the work and development of project team members.
  • Build internal and external relationships with key suppliers, customers, and internal service providers, with an emphasis on facilitating successful job/role responsibilities.
  • Respect and adhere to McKesson Standards, Policies, and Procedures.
  • Meet job performance standards and objectives outlined in the progress and appraisal guidelines.


Section C - Position Requirements

Minimum Qualifications :-

  • 8+ years of hands-on experience in enterprise infrastructure or systems engineering roles supporting large-scale, business-critical environments and Bachelor's degree in Computer Science, Computer Engineering, or a related discipline, or equivalent hands-on industry experience.


Knowledge:
  • expertise in enterprise operating systems, Microsoft Azure, VMware, and enterprise storage platforms, with strong experience designing, building, operating, and troubleshooting hybrid architectures across on-premises and Azure environments.
  • Proven track record of executing large-scale server and workload migrations from on-premises environments to hybrid and public cloud platforms.
  • Advanced proficiency in PowerShell scripting to automate infrastructure provisioning, configuration, migration activities, and ongoing operational tasks.
  • Strong working knowledge of application architecture and deployment processes, with the ability to align infrastructure design and implementation to application and business requirements.


Ability to:
  • Lead complex infrastructure modernization and migration initiatives, driving technical execution from design through implementation across on-premises, Azure Local, and hybrid Azure environments.
  • Apply strong engineering judgment to plan, build, and implement infrastructure solutions that meet enterprise requirements for security, reliability, performance, and compliance.
  • Anticipate and manage technical risks and dependencies throughout infrastructure and migration projects, ensuring stable implementations with minimal operational disruption.
  • Serve as a post-implementation escalation point to analyze, troubleshoot, and remediate infrastructure issues when required, ensuring long-term solution stability and resilience.
  • Operate with a high degree of ownership and accountability, independently prioritizing work, managing deliverables, and executing within defined project timelines and change windows.
  • Collaborate effectively with engineering, architecture, application, operations, and cybersecurity teams to deliver end-to-end infrastructure solutions aligned with McKesson standards.
  • Demonstrate clear and effective written and verbal communication skills in English, with the ability to articulate technical designs, risks, implementation outcomes, and recommendations to both technical and non-technical stakeholders.


We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For more information regarding benefits at McKesson, please click here.

Our Base Pay Range for this position

$99,100 - $132,100

McKesson has become aware of online recruiting-related scams in which individuals who are not affiliated with or authorized by McKesson are using McKesson's (or affiliated entities, like CoverMyMeds or RxCrossroads) name in fraudulent emails, job postings or social media messages. In light of these scams, please bear the following in mind:

McKesson Talent Advisors will never solicit money or credit card information in connection with a McKesson job application.

McKesson Talent Advisors do not communicate with candidates via online chatrooms or using email accounts such as Gmail or Hotmail. Note that McKesson does rely on a virtual assistant (Gia) for certain recruiting-related communications with candidates.

McKesson job postings are posted on our career site: careers.mckesson.com.

About McKesson

McKesson Corporation provides medicines, pharmaceutical supplies, information and care management products and services across the healthcare industry. The Company operates in two segments. The McKesson Distribution Solutions segment delivers ethical drugs, medical-surgical supplies and equipment and health and beauty care products throughout North America. This segment also provides specialty pharmaceutical solutions for biotech and pharmaceutical manufacturers, sells financial, operational and clinical solutions for pharmacies (retail, hospital, long-term care) and provides consulting, outsourcing and other services. The McKesson Technology Solutions segment delivers enterprise-wide clinical, patient care, financial, supply chain, strategic management and software solutions. In July 2011, the Company acquired Portico Systems from Safeguard Scientifics, Inc. On March 25, 2012, it acquired the independent banner and franchise businesses of Katz Group Canada Inc. McKesson Distribution Solutions delivers pharmaceuticals to retail pharmacies and institutional providers like hospitals and health systems. They operate pharmaceutical distribution centers across the country, serving customers in all 50 states. They also deliver a comprehensive offering of health care products, technology, equipment and related services to the alternate site market, including physician offices, surgery centers, long-term care facilities and home care businesses across the country. McKesson is currently the largest pharmaceutical distributor in North America. McKesson also operates McKesson Canada and has an equity holding in Nadro, a leading distributor in Mexico.

McKesson Careers

Join McKesson, a leading global healthcare company, and be part of a team that is redefining the future of healthcare. With a variety of job opportunities available, McKesson is the perfect place to advance your career, whether you're a seasoned professional or just starting out. Work You’ll Do At McKesson, we are committed to improving care in every setting—one product, one partner, one patient at a time. We’re seeking talented professionals to join our team and contribute to a culture of innovation, diversity, and leadership. Our employees are driven by a deep sense of purpose and a desire for continuous growth and improvement. Empower Your Future in Healthcare With positions ranging from internships to leadership roles, McKesson offers unparalleled employment opportunities to develop your skills and advance your career. Our commitment to diversity training ensures that all team members have the opportunity to thrive. Join a team where your skills will be honed, your professional growth will be supported, and where you can genuinely see the difference you make in the lives of patients around the world. Innovative Work Environment McKesson is at the forefront of healthcare innovation. Our team is constantly exploring new ways to improve patient outcomes and streamline care processes. This commitment to innovation is what sets us apart and what makes McKesson an exciting place to work. Career Development and Benefits McKesson believes in nurturing the potential of its employees through robust career development programs and comprehensive benefits designed to support your life and well-being. From leadership training to health and wellness benefits, we ensure our team members are equipped to meet their professional and personal goals. Explore Job Opportunities Whether you’re looking for an internship to kickstart your career, or a senior position to utilize your extensive experience, McKesson offers a range of opportunities. Explore our open positions and find where you can make a difference at McKesson. Stay Connected Join Our Team Search for open positions that match your skills and interests. We are looking for passionate, curious, and solution-driven team players who are ready to take the next step in their careers. Keep Up to Date Stay ahead with career tips, insider perspectives, and industry-leading insights you can put to use today—all from the people who work here. Networking and Professional Growth At McKesson, networking and professional growth are part of our everyday environment. We encourage our employees to connect, share, and learn from each other to foster personal and professional development. Job Alert Emails Personalize your subscription to receive job alerts, latest news, and insider tips tailored to your preferences. Discover the exciting and rewarding career opportunities that await you at McKesson. Join McKesson today and be part of a team that is dedicated to shaping the future of healthcare.
Learn more about McKesson
Size
58,000 employees
Market Cap
$53.7 billion
Industry
Net Income
-$4.1 billion
Founded
1833
5 Year Trend
+5.9%
Revenue
$237.6 billion
NASDAQ

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