AstraZeneca

Senior Forward Deployment Engineer - Cheminformatics & AI Modelling

AstraZeneca$144K — $216K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • 5-7 years of experience in software engineering, particularly with Python.
  • PhD in Chemistry preferred, Masters essential.
  • Proven experience in designing and deploying scalable software systems and services.
  • Strong problem-solving skills to translate complex scientific needs into software solutions.
  • Experience in data analysis and troubleshooting data pipelines.
  • Familiarity with relational databases and NoSQL technologies like PostgreSQL and Elasticsearch.
  • Excellent communication skills for cross-disciplinary collaboration.

Responsibilities

  • Partner with scientific teams to identify and address high-value engineering problems.
  • Design, build, and enhance software applications for drug discovery workflows.
  • Rapidly prototype and validate solutions with users, transitioning to robust production systems.
  • Integrate chemistry, cheminformatics, and data engineering to streamline scientific processes.
  • Collaborate with product and design teams to create impactful applications and services.
  • Implement platform development to enhance scalability and reliability of solutions.
  • Promote best practices in software engineering and mentor junior engineers.

Benefits

  • Health, dental, and vision coverage.
  • Paid time off for vacations, holidays, and leaves.
  • Qualified retirement programs available.
  • Eligibility for short-term incentive bonuses.
  • Equity-based awards for salaried roles.
Full Job Description
AstraZeneca are looking for a Senior Forward Deployed Engineer with a strong Chemistry Background based in our new Kendall Square R&D facilities to continue to build and enhance our next-generation multi-modality drug discovery platform.

In this role you will join a global team of engineers, cheminformaticians, architects, business analysts, and product managers in our Augmented Design Make Test Analyse (A-DMTA) organisation to support small molecule and new modality drug discovery as a Senior Forward Deployed Engineer.

The following will form part of the role:

  • Partner directly with scientists, product teams, and technical stakeholders to understand high-value problems and translate them into practical engineering solutions.


  • Design, build, deploy, and improve software applications, agentic solutions, MCP servers and tools and services that support key scientific workflows in drug discovery.


  • Prototype rapidly, validate with users, and evolve successful solutions into robust, scalable, production-grade systems.


  • Bridge chemistry, cheminformatics, data, and engineering to deliver integrated solutions across scientific and technical workflows.


  • Collaborate with product, design, data science, and scientific teams to build high-impact applications and services.


  • Plan, implement, and support platform and infrastructure development with the objective of improving scalability, reliability, performance, and usability.


  • Advocate for rigorous engineering practices and discipline, including code reviews, automated testing, logging, monitoring, documentation, and maintainability.


  • Help develop and promote a strong software engineering culture across multidisciplinary teams.


  • Stay on top of relevant technology trends, experiment with new approaches, participate in internal and external technology communities, and mentor other members of the engineering community.


  • Work with modern technology stacks in cloud environments to support scientific software delivery.


Required skills

  • Strong software engineering expertise in Python, including advanced object-oriented design and development of production-quality applications and services.


  • Experience designing, building, and deploying scalable software systems, APIs, and services in production environments.


  • Strong problem-solving and solution design skills, with the ability to translate complex scientific or business needs into practical software solutions.


  • Experience working directly with users, stakeholders, or domain experts to gather requirements, refine use cases, and deliver deployed solutions.


  • Ability to rapidly prototype solutions, validate them with users, and mature them into robust, maintainable production systems.


  • Background in chemistry (PhD preferred, Masters essential), with experience in cheminformatics, chemistry toolkits, chemistry search, and related algorithms.


  • Experience integrating systems, services, and data pipelines across complex technical environments.


  • Experience with relational databases such as PostgreSQL or Oracle, and/or NoSQL technologies such as Elasticsearch.


  • Experience in data analysis, including profiling, investigating, interpreting, and documenting data structures.


  • Experience in performance tuning SQL and understanding ETL or data integration pipelines.


  • Extensive experience troubleshooting data issues, analysing end-to-end data pipelines, and improving application or service performance.


  • Good experience in consuming or exposing web APIs.


  • Experience designing, developing, and deploying production-grade scalable applications using container technologies like Docker and Kubernetes.


  • Production experience delivering CI/CD pipelines using tools such as GitHub Actions, ArgoCD, or similar.


  • Experience creating and evaluating engineering architecture in the cloud.


  • Excellent verbal and written communication skills for effective collaboration with engineers, testers, architects, product managers, scientists, and other stakeholders.


  • Ability to work effectively in fast-moving and ambiguous environments, with ownership of delivery from problem definition through deployment and iteration.


The following skills would be advantageous for your application but are not considered essential:

  • Experience working with AWS.


  • DevOps experience, including deployment workflows and monitoring tools such as Grafana, Prometheus, and GitHub Actions.


  • Working knowledge of Scrum or Agile delivery.


  • Product ownership or technical leadership experience, with strong stakeholder communication and management.


  • Exposure to AI/ML-enabled applications in production, particularly where these are embedded within broader scientific or engineering platforms.


  • Development of agentic systems, MCP servers or tools


  • Specification-driven development


The annual base pay (or hourly rate of compensation) for this position ranges from $144,648.80 - 216,973.20 USD Annual. Our positions offer eligibility for various incentives-an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

Date Posted
12-ago-2026

Closing Date
10-sept-2026

About AstraZeneca

AstraZeneca is a British-Swedish multinational pharmaceutical company that specializes in the research, development, and manufacturing of prescription drugs. The company was formed in 1999 through the merger of Astra AB and Zeneca Group plc. AstraZeneca's products are used to treat a wide range of medical conditions, including cancer, cardiovascular disease, respiratory disease, and diabetes. The company has operations in over 100 countries and employs more than 76,000 people worldwide. AstraZeneca is committed to developing innovative medicines that improve the health and well-being of people around the world.
Learn more about AstraZeneca
Size
83,100 employees
Market Cap
$211.5 billion
Industry
Net Income
$3.1 billion
Founded
1999
5 Year Trend
+10.2%
Revenue
$26.6 billion
NASDAQ

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