Astellas Pharma US, Inc

Scientist I, Ophthalmology Research

Astellas Pharma US, Inc$94K — $135K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • PhD in Ophthalmology, Neuroscience, Biology, Pharmacology, or related field (0-3 years experience); OR MS with 5+ years; OR BS with 8+ years experience.
  • Hands-on in vivo research experience.
  • Experience with animal models, specifically rats or mice.
  • Research background in ophthalmology drug discovery or retinal biology.
  • Familiarity with therapeutics such as biologics, gene therapy or small molecules.
  • Strong organizational skills and attention to detail.

Responsibilities

  • Conduct in vivo pharmacology studies for ophthalmology indications.
  • Perform experimental activities, including animal procedures and clinical assessments.
  • Analyze and present experimental data with senior scientist guidance.
  • Contribute to study design and protocol development.
  • Support internal and external studies with cross-functional teams.
  • Maintain laboratory records and documentation per company standards.
  • Communicate scientific results through presentations and reports.

Benefits

  • Medical, Dental and Vision Insurance
  • Generous Paid Time Off including national holidays and year-end shutdown
  • 401(k) match and annual company contribution
  • Company paid life insurance
  • Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
  • Long Term Incentive Plan for eligible positions
  • Company fleet vehicle for eligible positions
  • Referral bonus program
Full Job Description
Scientist I, Ophthalmology Research

Purpose & Scope

The Scientist I, Ophthalmology Research supports the design, execution, and analysis of in vivo ophthalmology research studies that advance therapeutic programs from discovery through early development. The incumbent will generate high-quality data through hands-on laboratory work and collaborate within the broader research team to support program objectives. This is a bench-based role that provides opportunities to develop scientific and technical expertise in ophthalmology research and drug discovery.

Role and Responsibilities
  • Conduct in vivo pharmacology studies to evaluate therapeutic candidates across ophthalmology indications.
  • Perform hands-on experimental activities including animal procedures such as intraocular dosing (e.g. subretinal/intravitreal injection), clinical assessments, functional/efficacy evaluation, tissue collection, and other study-related techniques.
  • Analyze, interpret, document, and present experimental data with guidance from senior scientists.
  • Contribute to study design, protocol development, troubleshooting, and execution of research plans.
  • Assist with internally and externally conducted studies, including collaborations with cross-functional teams and contract research organizations.
  • Maintain accurate laboratory records, notebooks, and study documentation in accordance with company standards.
  • Communicate scientific results through presentations, reports, and team discussions.
  • Contribute to a collaborative, inclusive, and scientifically rigorous work environment by sharing knowledge and working effectively with team members.
  • Remain current with relevant scientific literature, technologies, and emerging approaches in ophthalmology research and drug discovery.


Required Qualifications
  • PhD in Ophthalmology, Neuroscience, Biology, Pharmacology, or a related scientific discipline with 0-3 years of relevant postdoctoral and/or industry research experience; OR
  • MS degree with 5+ years of relevant research experience; OR
  • BS degree with 8+ years of relevant research experience.
  • Hands-on experience conducting in vivo research studies and analyzing experimental data.
  • Experience working with animal models (rat and/or mouse) and laboratory research techniques.
  • Research experience in ophthalmology drug discovery, retinal biology, or related disciplines.
  • Familiarity with one or more therapeutic modalities, including biologics, gene therapy, cell therapy, RNA therapeutics, or small molecules.
  • Strong organizational skills, attention to detail, and ability to maintain accurate documentation.
  • Demonstrated ability to work effectively in a collaborative team environment.
  • Strong written, verbal, and presentation communication skills.

Preferred Qualifications

  • Interocular dosing techniques in rodents (i.e. subretinal injection, intravitreal injection, etc.)
  • Experience with ocular imaging and visual function assessments, including OCT, fundus imaging, ERG, optomotor response, or related techniques.
  • Experience with ocular histology, tissue processing, microscopy, and image analysis.
  • Familiarity with translational research and drug discovery.
  • Experience collaborating with external laboratories, CROs, or academic partners.
  • Demonstrated ability to learn new techniques and adapt to changing project priorities.

Location and Working Environment
  • This position is based in Westborough, MA and requires on-site work.
  • The incumbent is expected to actively participate in experimental design, study execution, data analysis, and scientific discussions.
  • The role involves collaboration with internal and external stakeholders in a highly collaborative research environment.


Salary Range

$94,570 - $135,100 (Final compensation will be determined based on a variety of factors, including but not limited to skills, experience and organizational equity considerations)

Benefits:
  • Medical, Dental and Vision Insurance
  • Generous Paid Time Off options, including Vacation and Sick time, plus national holidays including year-end shut down
  • 401(k) match and annual company contribution
  • Company paid life insurance
  • Annual Corporate Bonus and Quarterly Sales Incentive for eligible positions
  • Long Term Incentive Plan for eligible positions
  • Company fleet vehicle for eligible positions
  • Referral bonus program


#LI-TR1

About Astellas Pharma US, Inc

Astellas Pharma US, Inc is a pharmaceutical company that develops and markets drugs for the treatment of cancer, immunology, and urology. The company is a subsidiary of Astellas Pharma Inc, a Japanese pharmaceutical company. Astellas Pharma US, Inc was founded in 2005 and is headquartered in Northbrook, Illinois. The company has over 17,000 employees and operates in over 50 countries. Astellas Pharma US, Inc is committed to improving the health and well-being of patients through the development of innovative and effective therapies.
Learn more about Astellas Pharma US, Inc
Size
14,522 employees
Industry
Founded
2005
NASDAQ

Similar Jobs

More Jobs at Astellas Pharma US, Inc

More Pharmaceuticals & Biotech Jobs

Find similar Scientist I, Ophthalmology Research jobs: