Roche

Scientist 2, Clinical Cellular Biomarkers

Roche$87K — $161K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree with 2-5 years, or Master's degree with 0-2 years of experience in relevant scientific disciplines like Immunology or Bioinformatics.
  • Strong hands-on flow cytometry experience, with a focus on designing and troubleshooting high-parameter panels.
  • Proven ability to manage relationships with cross-functional stakeholders in a dynamic team setting.
  • Exceptional verbal and written communication skills, capable of simplifying complex data into actionable insights.
  • Experience with advanced analysis tools and programming, including familiarity with coding languages like R and Python.

Responsibilities

  • Independently design and validate complex flow cytometry biomarker assays for clinical development.
  • Manage the outsourcing of assays to Contract Research Organizations, ensuring high-quality assay transfer.
  • Perform computational analysis and visualizations to derive biological insights from assay results.
  • Present findings to laboratory and study teams clearly and effectively.
  • Collaborate with biomarker scientists and cross-functional stakeholders to align assay strategies with study goals.

Benefits

  • Comprehensive health insurance options.
  • Flexible work hours and potential for hybrid remote working arrangements.
  • Professional development opportunities and support for ongoing education.
Full Job Description
Scientist 2, Clinical Cellular Biomarkers

Department Summary

The Clinical Cellular Biomarkers (C2B) group in the Operations, Diagnostics, and Technology (ODT) organization within the Translational Medicine (TM) department in gRED is seeking a highly motivated, experienced, and collaborative Scientist 2 to support clinical development efforts. As a Scientist 2, you will provide critical translational science expertise to inform clinical development, identifying insights that advance personalized healthcare, ensuring the right therapeutic reaches the right patient at the right dose.

In this role, you will spearhead the design, validation, and execution of high-parameter clinical flow cytometry biomarker assays. Furthermore, you will apply your scientific knowledge in immunology and oncology to evaluate generated datasets and address key biomarker inquiries by utilizing analytical platforms, programming, and AI-enabled tools.

The Opportunity

In this role, you will independently design, optimize, and validate complex, high-parameter flow cytometry biomarker assays supporting one or more molecules and indications in the non-oncology and oncology indications. You will oversee and manage the outsourcing of flow cytometry assays to Contract Research Organizations (CROs), ensuring high-quality assay transfer, validation, and data delivery. You will be responsible for key analysis of the deployed assays and expected to perform various computational analysis and visualizations to extrapolate key biological insights. You will regularly present these findings to laboratory groups and broader study teams. You will continuously partner and collaborate effectively with multiple cross-functional stakeholders, biomarker scientists, study teams, and external research partners to align cytometry strategies with study goals. In addition to supporting key molecules, you will additionally support prioritized translational research projects.

Who You Are

Required Qualifications

  • Education & Experience: Required qualifications include 2-5 years of relevant experience with a Bachelor's degree or 0-2 years of relevant experience with a Master's degree in Immunology, Molecular Biology, Cell Biology, Genomics, Bioengineering, Bioinformatics, or a related discipline.
  • Flow Cytometry Expertise: Strong hands-on laboratory experience in cell biology and flow cytometry, with a proven track record of designing, validating, and troubleshooting cytometry panels on diverse human sample types (PBMCs, BMMCs, whole blood, etc.). Experience with the cytometry analysis tools is required.
  • Collaborative Stakeholder Management: Excellent interpersonal skills with a proven ability to coordinate with multiple cross-functional stakeholders in a fast-paced, matrixed team environment.
  • Communication & Presentation Skills: Strong written, oral, and presentation skills, with a demonstrated ability to translate complex data into digestible and actionable scientific insights.

Preferred Qualifications

  • Flow Cytometry Expertise: Highly preferable to have experience designing, validating, and troubleshooting high-parameter (30+) panels. Demonstrated expertise in both spectral and conventional cytometry instrumentation, with specific hands-on experience on platforms such as the Cytek Aurora and BD Lyric.
  • Advanced Analysis Software: High proficiency in advanced cytometry analysis platforms such as OMIQ is highly desirable.
  • Coding & AI Utilization: Demonstrated familiarity or experience using various computational tools such as R and Python for analysis and visualizations. Quick adopter of various AI-enabled tools and coding agents such as Claude Code.
  • CRO Partner Experience: Experience working with Contract Research Organization (CRO) partners is highly desirable. This includes experience with assay outsourcing, assay validation, tech transfer, and managing external data quality.

Relocation benefits are not available for this job posting.

The expected salary range for this position based on California is 87 000,00 - 161 600,00 USD Annual Annual.Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.A discretionary annual bonus may be available based on individual and Company performance.This position also qualifies for the benefits detailed at the link provided below.

About Roche

Roche Holding AG is a Swiss multinational healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, Roche Holding AG, has bearer shares listed on the SIX Swiss Exchange. The company headquarters are located in Basel. Roche is the largest pharmaceutical company in the world, and the leading provider of cancer treatments globally. The company also produces a range of diagnostic tests for medical professionals and patients. Roche was one of the first companies to bring targeted treatments to patients. In 2019, Roche had over 100,000 employees worldwide, and generated revenue of CHF 61.5 billion.
Learn more about Roche
Size
100,920 employees
Industry
NASDAQ

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