Massachusetts Institute of Technology

Research Scientist 1

Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • Ph.D. in Computational Biology, Bioinformatics, Computer Science, Neuroscience, or related field
  • Minimum of two years of relevant research experience, including graduate work
  • Experience with single-cell and/or spatial omics data in human or mouse brain studies
  • Proficiency in programming languages such as Python and R
  • Familiarity with AI/ML approaches for biological data
  • Evidence of potential for original or collaborative scholarship

Responsibilities

  • Lead computational analyses of large-scale single-cell and spatial multi-omic datasets
  • Design and execute computational experiments
  • Interpret results to uncover cell-type-specific mechanisms
  • Investigate pathway-level mechanisms driving disease risk and progression
  • Collaborate with principal investigators on research objectives

Benefits

  • Opportunity to work with cutting-edge technology in artificial intelligence and neuroscience
  • Collaborative work environment with leading experts in the field
  • Involvement in impactful research contributing to understanding neurodegenerative diseases
  • Potential for original scholarship and visibility through publications and projects
Full Job Description
Posting Description
RESEARCH SCIENTIST 1, Computer Science and Artificial Intelligence Lab, will lead computational analyses of large-scale single-cell and spatial multi-omic datasets derived from human postmortem brain samples to study the molecular and cellular mechanisms underlying neurodegenerative and neuropsychiatric diseases. Working in collaboration with the PIs, the scientist will design, execute, and interpret computational experiments to uncover cell-type-specific and pathway-level mechanisms driving disease risk, progression, and resilience.

Full job description is available here: https://www.dropbox.com/scl/fi/ogp0biw4hs9fok3qqd0ni/Research-Scientist-1-JD.pdf?rlkey=v3u6zp7fey8devovmg10fq3hh&st=bntsjvjf&dl=0

Job Requirements REQUIRED: A Ph.D. in Computational Biology, Bioinformatics, Computer Science, Neuroscience, or a related field; a minimum of two years of relevant research experience, which may include graduate work; demonstrated experience with single-cell and/or spatial omics data, particularly in human or mouse brain studies; proficiency in programming languages such as Python and R, with experience in high-performance or cloud-based computing; familiarity with AI/ML approaches (e.g., dimensionality reduction, autoencoders, or graph-based learning) for biological data; and evidence of potential for original or collaborative scholarship, demonstrated through publications, software contributions, or impactful analytical work. PREFERRED : Experience contributing to data portals, open-source pipelines, or collaborative computational infrastructure.

Some evening/night/weekend work may be required when working on deadlines.

4/17/2026

About Massachusetts Institute of Technology

The Massachusetts Institute of Technology (MIT) is a private research university located in Cambridge, Massachusetts. MIT is a member of the Association of American Universities (AAU) and is classified among "R1: Doctoral Universities – Very high research activity". The university is known for its strong emphasis on scientific and technological research and its engineering programs. MIT was founded in 1861 and has a long history of innovation and entrepreneurship. The university has produced numerous Nobel laureates, Rhodes Scholars, and MacArthur Fellows.
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