Frontier Medicines is seeking a highly motivated Research Associate II to join the In Vivo Phamacology group. This role combines hands-on in vivo pharmacology work in our South San Francisco vivarium with translational research responsibilities, The successful candidate will work as part of a multidisciplinary team in a fast-paced drug-discovery environment, contributing to both internal preclinical studies and translational medicine activities.
What will you be doing?In Vivo Pharmacology:- Execute in vivo experiments to evaluate the efficacy and PKPDTE relationship of novel compounds across multiple programs.
- Conduct murine-based tumor model studies, including animal handling, dosing via multiple routes, and health monitoring
- Perform mouse necropsies, tissue harvest, blood collection, and sample processing for downstream analysis
- Formulate and prepare test substances for in vivo administration
- Maintain sample inventory and coordinate sample shipment to designated internal and external teams
- Ensure animal welfare and maintain compliance with IACUC, GLP, and non-GLP policies through detailed electronic laboratory notebook documenting
- Maintain a clear, detailed electronic laboratory notebook to document all experiments and finding
- Knowledge in cell culture
Translational Research:- Manage mouse tumor model activities at CROs and through external collaborations.
- Design, coordinate, and conduct in vivo mouse tumor model studies in collaboration with the Translational Medicine team.
- Manage and support in vivo studies across multiple programs concurrently.
- Perform data analysis and prepare presentations for internal and external audiences.
- Effectively communicate with colleagues, collaborators, and stakeholders; engage in the science beyond the experimental objective.
RequirementsWhat are we looking for?Required:- BS or MS in a biological science (e.g., animal science, pharmacology, cellular biology, biomedical sciences, or related discipline).
- At least 2-4 years of relevant experience in pharma/biotech, including in vivo pharmacology and/or translational medicine settings.
- Experience in cancer biology, oncology drug discovery project teams, rodent cancer model development, and drug testing.
- Experience with in vivo techniques, including dosing, blood collection, and model development.
- Strong organizational, communication, and presentation skills.
- Ability to work independently, manage multiple tasks effectively, and thrive in a dynamic start-up environment.
- Willingness to learn new techniques and follow directions precisely.
- A commitment to excellence, high-quality science, and a professional working environment.
- Legally authorized to work in the US.
Benefits- Health Care Plan (Medical, Dental & Vision)
- Retirement Plan (401k, IRA)
- Life Insurance (Basic, Voluntary & AD&D)
- Paid Time Off (Vacation, Sick & Public Holidays)
- Family Leave (Maternity, Paternity)
- Short Term & Long Term Disability
- Training & Development
- Free Food & Snacks
- Wellness Resources
- Stock Option Plan
The salary range for this role is $75,000 - $95,000.
The level and compensation for this role will be determined based on the candidate's qualifications, experience, and expertise. Compensation for the role will depend on a number of factors, including candidates' qualifications, skills, competencies and experience. Frontier offers a competitive total rewards package which includes healthcare coverage, 401k and a broad range of other benefits.
This compensation and benefits information is based on Frontier's knowledge as of the date of publication, and may be modified in the future.
