Full Job Description
We are seeking a highly motivated Process Chemist III to join our Process Development team. The successful candidate will lead the development, optimization, and scale-up of synthetic processes for small molecules, linker-payloads, intermediates, and related compounds from early development through cGMP manufacturing. This role requires strong technical expertise, excellent problem-solving skills, and the ability to collaborate effectively with cross-functional teams.
Responsibilities
• Design, execute, and optimize synthetic routes for small molecules, intermediates, and complex drug-linker compounds.
• Develop scalable, robust, and cost-effective manufacturing processes suitable for pilot plant and cGMP production.
• Plan and perform laboratory experiments, analyze data, and interpret results to guide process improvements.
• Troubleshoot challenging synthetic and scale-up issues using sound scientific principles.
• Collaborate with Analytical Development, Manufacturing, MSAT, Quality, Supply Chain, and Project Management teams to ensure successful technology transfer and manufacturing campaigns.
• Prepare technical reports, batch records, process descriptions, risk assessments, and technology transfer documentation.
• Maintain accurate laboratory notebooks and ensure documentation complies with company and regulatory standards.
• Mentor junior scientists and provide technical guidance on experimental design and process development.
• Support client meetings by presenting technical data and project updates.
• Contribute to continuous improvement initiatives focused on safety, quality, efficiency, and sustainability
Qualifications
• Ph.D. in Organic Chemistry with 2+ years of industrial experience, or
• M.S. in Organic Chemistry with 5+ years of industrial experience, or
• Strong knowledge of synthetic organic chemistry and process development.
• Experience with reaction optimization, impurity control, and process scale-up.
• Experience with analytical techniques such as UPLC, HPLC, LC-MS, GC, and NMR.
• Excellent scientific writing, communication, and presentation skills.
• Demonstrated ability to manage multiple projects in a fast-paced environment.
Preferred
• Experience in pharmaceutical, biotechnology, or CDMO environments.
• Experience supporting cGMP manufacturing campaigns and technology transfer.
• Experience with linker-payload synthesis, peptide coupling chemistry, or highly potent compounds is desirable.
Physical Requirements
• Ability to stand for 1-2 hours at a time, sit for 2 to 3 hours at a time.
• Frequently lift and or move objects up to 30 pounds.
• Stand/walk during entire length of shift.
• Use arms, hands, and fingers to handle, feel or reach.
• Ability to climb, balance, stoop, kneel, crouch, or crawl.
• Visual abilities including near and far sight, color, peripheral vision, depth, and ability to focus.
• Ability to work with a PAPR and gown during work with high potent materials.
FLSA: Exempt