Merck & Co, Inc

Principal Scientist, Drug Discovery

Merck & Co, Inc$169K — $267K *
Pharmaceuticals & Biotech
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • DVM/VMD and PhD in experimental pharmacology required
  • 8+ years in drug discovery or preclinical research focusing on in vivo pharmacology
  • Advanced knowledge of pharmacology and disease mechanisms
  • Expert in oncology, diabetes, respiratory & immunology, cardiology, pain & inflammation, reproduction, drug delivery, or biotechnology
  • Experience with GLP, GCP, and GMP regulations
  • Proficient in project management including budgets and timelines
  • Strong communication and presentation skills

Responsibilities

  • Identify new molecular entities and technologies for animal health
  • Lead research programs from ideation through proof-of-concept
  • Interface with internal and external stakeholders
  • Manage resources across multiple research areas
  • Prepare and submit patent applications for new discoveries
  • Facilitate collaborations with external partners and academic institutions
  • Ensure compliance with regulatory standards in research processes

Benefits

  • Comprehensive medical, dental, and vision insurance for employees and families
  • 401(k) retirement plan with company contributions
  • Paid holidays, vacation, and sick leave
  • Potential for annual bonuses and long-term incentives
  • Hybrid work model allowing remote work on Fridays
  • Commitment to inclusivity and diverse workplace culture
Full Job Description
Job Description

The Principal Scientist, Drug Discovery in our Research and Development Department will be responsible for identifying new molecular entities and technologies for use in animal health from our Company Laboratories or from external partners such as human pharma or biotech companies as well as academia. The successful candidate will be a key driver to advance novel targets and will lead these research programs from ideation through the early research and proof-of-concept phase up to the development stage. She/he/they will interface with researchers and senior management throughout the organization as well as external partners and operate within a matrix structure to garner resources for the necessary research work (Medicinal and Process Chemistry, in vitro Pharmacology, Pharmacokinetics, Disease Models, Formulation Development, Safety & Toxicology). The position will report directly to the Distinguished Scientist and Global Head, our Company's Research & Development Liaison and Discovery - Non-infectious Diseases.

Education:
  • Required: DVM/VMD, as well as a PhD in experimental pharmacology


Required Experience:
  • Minimum of 8 years industry or pharmaceutical research experience in drug discovery or preclinical research with a focus on in vivo pharmacology
  • Advanced and thorough scientific knowledge in pharmacology, disease mechanisms and related preclinical models
  • Expertise in one of the following fields: oncology, diabetes, respiratory & immunology, cardiology, pain & inflammation, reproduction, drug delivery or biotechnology
  • Knowledge of regulatory aspects of pharmaceuticals including GLP, GCP and GMP
  • Ability to manage multiple projects, including budgets, contracts, and timelines
  • Ability to independently plan, recommend and complete research programs
  • Excellent communication and interpersonal skills
  • Effective creator of executive level presentations and documents
  • Experience in preparing patent applications in support of patent coverage of research efforts
  • 10 % Travel


Preferred Experience:
  • Board certification in Pharmacology
  • Project management skills within pharmaceuticals
  • Experience in developing and managing collaborations with outsource providers, vendors, contractors and academic institutions
  • Experience in working with business development to identify and license external technology opportunities


Location:
  • Our Company's Animal Health Headquarters, Rahway, NJ


Required Skills:
Adaptability, Assay Development, Biochemical Assays, Cell Culture Techniques, Communication, Detail-Oriented, Ethical Compliance, Functional Genomics, In Vivo Models, Leading Project Teams, Molecular Biology Techniques, Persuasion, Professional Networking, Protein Biochemistry, Protein Purifications, Science, Social Collaboration, Virology

Preferred Skills:

Current Employees apply HERE

Current Contingent Workers apply HERE

Employee Status:
Regular

Relocation:
Domestic

VISA Sponsorship:
No

Travel Requirements:
10%

Flexible Work Arrangements:
Hybrid

Shift:
Not Indicated

Valid Driving License:
No

Hazardous Material(s):
N/A

Job Posting End Date:
07/15/2026
*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

About Merck & Co, Inc

Schering-Plough Corporation is a major U.S.-based manufacturer of pharmaceuticals. It operates in three segments: Prescription Pharmaceuticals, Animal Health, and Consumer Health Care. Schering-Plough develops products targeting on allergy, cancer, hepatitis, cardiovascular, central nervous system, respiratory system, and more.  It was founded in 1851 by Ernst Christian Friedrich Schering as Schering AG in Germany. Schering-Plough manufactured several pharmaceutical drugs, the most well-known of which were the allergy drugs Claritin and Clarinex, an anti-cholesterol drug Vytorin, and a brain tumor drug Temodar. It also developed drugs targeting on central nervous system and the respiratory system. Schering Plough also owned and operated the major foot care brand name Dr. Scholl's and the skin care line Coppertone. These also became a part of the new company. Schering-Plough was a full member of the European Federation of Pharmaceutical Industries and Associations (EFPIA), a membership which is also maintained by the new Merck.

Merck & Co, Inc Careers

Join the visionary team at Merck & Co, Inc, a global leader in healthcare dedicated to advancing the world of medicine. As part of our professional community, you'll find dynamic job opportunities that foster innovation and leadership across various fields. Merck & Co, Inc is not just a company; it's a place where you can make a difference.

Work You’ll Do

At Merck & Co, Inc, we are committed to improving global health through groundbreaking research and innovative healthcare solutions. Our team is at the forefront of developing new therapies and vaccines that significantly impact public health worldwide. By joining us, you will collaborate with some of the brightest minds in the industry, using your skills to contribute to projects that save and improve lives around the globe.

Explore Career Paths

Whether you're seeking an internship, a graduate opportunity, or a professional position, Merck & Co, Inc offers a range of career paths in environments that promote rapid professional growth and development. Explore job opportunities in research, digital transformation, manufacturing, and more, all while benefiting from a culture that supports diversity and inclusion.

Innovate and Lead

Merck & Co, Inc is an ideal environment for those who lead with curiosity and the drive to innovate. Our leadership is committed to fostering a culture where inventive thinking and collaboration are encouraged, making it a perfect place for professionals who seek to make an impact through their work.

Develop Your Skills

With Merck & Co, Inc, you are not just getting a job; you're gaining access to unparalleled career development opportunities. Enhance your skills through diverse training programs, workshops, and continuous learning courses designed to help you grow at every stage of your career.

Benefits and Culture

We understand that our employees are our greatest asset, which is why we offer competitive benefits designed to support the health and well-being of you and your family. From comprehensive health care coverage and retirement plans to flexible working conditions and wellness programs, our benefits package is designed to meet the diverse needs of our team members.

Join Our Team

Ready to advance your career at Merck & Co, Inc? Search open positions that match your skills and interests. We are continuously hiring and looking for passionate, creative, and solution-driven team players. Prepare your resume, sharpen your interview skills, and become part of a company that's dedicated to making a difference.

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Learn more about Merck & Co, Inc
Size
68,000 employees
Market Cap
$282.6 billion
Industry
Net Income
$7 billion
Founded
1668
5 Year Trend
+4.1%
Revenue
$47.9 billion
NASDAQ

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