Merck & Co, Inc

Postdoctoral Research Fellow, NMR Spectroscopy

Merck & Co, Inc • $82K — $92K *
Pharmaceuticals & Biotech
Less than 5 years of experience
Job Overview by Ladders

Qualifications

  • PhD in Chemistry, Biochemistry, Pharmaceutical Sciences, Chemical Engineering, or related field (or expected by Spring 2027)
  • Expertise in NMR spectroscopy and complex data interpretation
  • Strong publication record in peer-reviewed journals or conference presentations
  • Ability to conduct independent research in a collaborative setting
  • Familiarity with molecular modeling and machine learning techniques

Responsibilities

  • Plan and execute independent NMR spectroscopy research on biologics
  • Develop and optimize NMR experiments for complex biomolecules
  • Create automated workflows for spectral feature detection and interpretation
  • Evaluate structure generation and chemical shift prediction methods, including AI and machine learning
  • Integrate NMR data with molecular dynamics for biomolecular characterization
  • Apply methods to therapeutic proteins and other pharmaceutical systems
  • Collaborate with cross-functional teams and publish research findings

Benefits

  • Comprehensive medical, dental, and vision insurance for employees and families
  • Retirement benefits including 401(k)
  • Paid holidays and vacation days
  • Compassionate and sick leave
  • Eligibility for annual bonuses and long-term incentives
Full Job Description
Job Description

Our company is seeking a highly motivated Postdoctoral Research Fellow to join Pharmaceutical Analysis & Digital Technologies (PADT) in Rahway, New Jersey. This is an exciting opportunity to develop next-generation NMR spectroscopy approaches for the structural characterization of biologics and other complex pharmaceutical molecules. The successful candidate will lead publication-oriented research that expands biomolecular NMR beyond conventional biophysical measurements toward detailed, atomistic interpretation of natural-abundance NMR spectra.

Responsibilities:
  • Plan and execute independent research in NMR spectroscopy applied to biologics.
  • Develop and optimize NMR experiments and spectral analysis strategies for complex biomolecules and pharmaceutical formulations.
  • Create automated workflows to detect and interpret distinctive chemical shifts, linewidths, couplings, and other diagnostic spectral features.
  • Evaluate structure generation methods and chemical shift prediction approaches, including AI, machine learning, and physics-based models.
  • Integrate NMR data with molecular dynamics and iterative structural refinement to characterize biomolecular conformational ensembles.
  • Apply developed methods to therapeutic proteins, novel biologic modalities, peptides, adjuvants, and other pharmaceutically relevant systems.
  • Collaborate with teams in PADT, Large Molecule Analytical, Pharmaceutical Sciences & Device Development, and Protein Sciences and Biophysics.
  • Publish findings in peer-reviewed journals and present research at scientific meetings.


Education:
  • Must currently hold a PhD OR
  • Receive a Ph.D. no later than spring 2027
  • Ph.D. in Chemistry, Biochemistry, Pharmaceutical Sciences, Chemical Engineering, or a related discipline.


Required Experience and Skills:
  • Expertise in NMR spectroscopy and interpretation of multidimensional or complex NMR data.
  • Strong record of scientific achievement, including peer-reviewed publications or conference presentations.
  • Ability to design, execute, analyze, and communicate independent research in a collaborative environment.


Preferred Experience and Skills:
  • Experience in biomolecular NMR or structural biology.
  • Experience with Python, C/C++, Rust, or other scientific programming languages.
  • Knowledge of molecular modeling, machine learning, and generative AI.


The salary range for this role is: $82,000- $92,000

This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An employee's position within the salary range will be based on several factors including, but not limited to relevant education, qualifications, certifications, experience, skills, geographic location, government requirements, and business or organizational needs.

The successful candidate will be eligible for annual bonus and long-term incentive, if applicable.

We offer a comprehensive package of benefits. Available benefits include medical, dental, vision healthcare and other insurance benefits (for employee and family), retirement benefits, including 401(k), paid holidays, vacation, and compassionate and sick days.

Required Skills:
Analytical Chemistry, Biochemistry, Chemistry, Molecular Dynamics (MD), Molecular Modeling, Nuclear Magnetic Resonance Spectroscopy (NMR), Scientific Literacy, Scientific Research

Preferred Skills:

Current Employees apply HERE

Current Contingent Workers apply HERE

US and Puerto Rico Residents Only:

Our company is committed to inclusion, ensuring that candidates can engage in a hiring process that exhibits their true capabilities. Please click here if you need an accommodation during the application or hiring process.

Search Firm Representatives Please Read Carefully
Merck & Co., Inc., Rahway, NJ, USA, also known as Merck Sharp & Dohme LLC, Rahway, NJ, USA, does not accept unsolicited assistance from search firms for employment opportunities. All CVs / resumes submitted by search firms to any employee at our company without a valid written search agreement in place for this position will be deemed the sole property of our company. No fee will be paid in the event a candidate is hired by our company as a result of an agency referral where no pre-existing agreement is in place. Where agency agreements are in place, introductions are position specific. Please, no phone calls or emails.

Employee Status:
Regular

Relocation:
Domestic

VISA Sponsorship:
Yes

Travel Requirements:
10%

Flexible Work Arrangements:
Not Applicable

Shift:
Not Indicated

Valid Driving License:
No

Hazardous Material(s):
N/A

Job Posting End Date:
10/12/2026
*A job posting is effective until 11:59:59PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

About Merck & Co, Inc

Schering-Plough Corporation is a major U.S.-based manufacturer of pharmaceuticals. It operates in three segments: Prescription Pharmaceuticals, Animal Health, and Consumer Health Care. Schering-Plough develops products targeting on allergy, cancer, hepatitis, cardiovascular, central nervous system, respiratory system, and more.  It was founded in 1851 by Ernst Christian Friedrich Schering as Schering AG in Germany. Schering-Plough manufactured several pharmaceutical drugs, the most well-known of which were the allergy drugs Claritin and Clarinex, an anti-cholesterol drug Vytorin, and a brain tumor drug Temodar. It also developed drugs targeting on central nervous system and the respiratory system. Schering Plough also owned and operated the major foot care brand name Dr. Scholl's and the skin care line Coppertone. These also became a part of the new company. Schering-Plough was a full member of the European Federation of Pharmaceutical Industries and Associations (EFPIA), a membership which is also maintained by the new Merck.

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Learn more about Merck & Co, Inc
Size
68,000 employees
Market Cap
$282.6 billion
Industry
Net Income
$7 billion
Founded
1668
5 Year Trend
+4.1%
Revenue
$47.9 billion
NASDAQ

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