Kymera Therapeutics

Medical Director or Senior Medical Director

Kymera Therapeutics • $300K — $380K *
Watertown, MA 02472In-Person
Pharmaceuticals & Biotech
Less than 5 years of experience
Today
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Job Overview by Ladders

Qualifications

  • MD or MD/PhD with substantial clinical development experience in dermatologic medicine.
  • Minimum 4 years of clinical drug development experience, including 2 years on dermatologic indications.
  • Experience with global regulatory agencies (e.g., FDA, EMA) and preparing submission documents.
  • Track record of designing and executing clinical trials (Phase I-III).
  • Strong knowledge of translational science and biomarkers in drug development.
  • Proven leadership ability in cross-functional team settings.
  • Demonstrated passion for developing first-in-class therapies.

Responsibilities

  • Serve as the clinical lead for one or more studies within the STAT6 program.
  • Integrate translational and biomarker data into clinical strategies.
  • Lead the design and implementation of clinical studies, focusing on safety and rigor.
  • Collaborate with academic institutions and external partners to advance clinical strategies.
  • Provide medical leadership to development and clinical teams.
  • Oversee safety monitoring and data review during trials, making protocol amendments as necessary.
  • Contribute to clinical and regulatory documents and assist in talent development.

Benefits

  • Comprehensive benefits package including annual bonuses and equity participation.
  • Opportunities for professional development and coaching.
  • Collaborative and science-driven work environment.
Full Job Description


How you'll make an impact:
  • Serve as the clinical lead for one or more studies within the STAT6 program.
  • Integrate translational and biomarker data into clinical strategy to refine patient selection and endpoint development.
  • Lead the design and implementation of clinical studies, ensuring scientific rigor and patient safety.
  • Collaborate with external partners, academic institutions, and consortia to advance the scientific and clinical development strategy.
  • Provide medical leadership to cross-functional teams, including development sub-teams and clinical study teams.
  • Provide medical oversight during clinical trial conduct, including safety monitoring, data review, and protocol amendments as needed.
  • Contribute to the development of clinical and regulatory documents (protocols, IBs, CSRs, regulatory submissions).
  • Contribute to hiring, coaching, and development of clinical development talent.
  • Represent Kymera in scientific, regulatory, and clinical forums, including interactions with KOLs, investigators, and advisory boards.

Skills and experience you'll bring:
  • MD or MD/PhD and substantial clinical development experience in developing medicines for dermatologic indications.
  • Minimum of 4 years of experience in clinical drug development, of which at least 2 years of experience is working on dermatologic indications or in programs with dermatologic endpoints.
  • Experience interacting with global regulatory agencies (e.g., FDA, EMA) and preparing briefing documents for regulatory submissions.
  • Proven track record in designing and executing clinical trials (Phase I-III) and contributing to successful regulatory interactions.
  • Strong understanding of translational science, biomarkers, and mechanistic drug development.
  • Demonstrated ability to lead cross-functional teams and manage multiple programs in parallel.
  • Entrepreneurial mindset and passion for advancing first-in-class therapies in a collaborative, science-driven environment.
  • Excellent leadership, communication, and collaborative skills; ability to thrive in a fast-paced, matrixed environment.


Compensation
  • Kymera offers a competitive compensation package that recognizes both results and capabilities through market-based, performance-driven pay.
  • The anticipated base salary range for this role is $300,000- $380,000, with eligibility for annual bonus, equity participation, and comprehensive benefits.
  • Actual salary is based on a holistic evaluation of the specific role/level as well as each candidate's depth of experience and the capabilities they bring to the position.

About Kymera Therapeutics

Kymera Therapeutics is a clinical-stage biopharmaceutical company that is focused on discovering and developing novel small molecule therapeutics that selectively degrade disease-causing proteins by harnessing the body's own natural protein degradation system. The company's proprietary targeted protein degradation platform, Pegasus, is designed to harness the body's natural protein recycling machinery to degrade disease-causing proteins, with a focus on undruggable and difficult-to-drug targets. Kymera's initial programs are focused on oncology and immunology, with a goal of delivering transformative therapies for patients with previously untreatable diseases. Kymera was founded in 2015 and is headquartered in Cambridge, MA.
Learn more about Kymera Therapeutics
Size
75 employees
Market Cap
$1.4 billion
Industry
Pharmaceuticals & Biotech
Founded
2017
NASDAQ
KYMR
* Ladders Estimates

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