Description of RoleCentessa is seeking a Manager, Clinical Supply Chain to support end-to-end planning, execution, and maintenance of uninterrupted clinical supply - including investigational product (IP), comparators, and ancillary materials - across assigned clinical programs. This role ensures compliance with GxP requirements, study timelines, and budgets while partnering cross-functionally with Clinical Operations, CMC, Quality, Regulatory, Finance, and external vendors. Reporting to the Senior Director, Clinical Supply Chain, the individual will build strong relationships with internal teams and third-party suppliers to align objectives and support successful trial execution, with particular attention to clinical forecasts, inventory systems, and IRT tools.
Key ResponsibilitiesClinical Supply Planning & Execution- Contribute to the development and execution of clinical supply strategies for early- to mid-phase clinical trials (Phase 1-3 as applicable).
- Manage clinical supply plans, demand forecasts, and inventory strategies - including tracking through Interactive Response Technology (IRT) systems - in alignment with protocol requirements and enrollment projections.
- Support packaging, labeling, distribution, and resupply activities for investigational products and comparators.
- Ensure on-time delivery of clinical supplies to depots and clinical sites globally.
Vendor & CDMO Management- Partner with Quality, Clinical, CMC, and external CDMOs to develop, review, and approve clinical labels, and support CDMO packaging/labeling schedules to ensure supply availability.
- Interact regularly with third-party providers to manage the logistics and licenses required to ship materials from manufacturing to bulk storage facilities, courier depots, and investigator sites.
- Collaborate with CMC and QA to facilitate the document transfer required for IP/QP release by CDMOs.
Quality & Compliance Support- Monitor shelf-life and expiry dating, and coordinate retest/extension activities with the analytical team to ensure continuous supply.
- Manage the investigation, reporting, and communication of outcomes from temperature excursions and product complaints.
- Support product recovery activities pending investigation of IP from investigator sites, as needed.
Cross-Functional Collaboration & Representation- Communicate effectively across functional areas, applying a solid working knowledge of clinical supply chain processes.
- Author Pharmacy Manuals for clinical studies, as needed.
- Represent Supply Chain in Clinical and CMC Sub-Team meetings
Qualifications- Bachelor's degree in engineering or science required.
- 3-5 years of biotech/pharma industry experience in clinical supply chain, including international experience, required.
- Working knowledge of clinical supply chain processes and GMP/GDP requirements.
- Experience coordinating cross-functional project teams and external vendors.
- Strong organizational, analytical, decision-making, and interpersonal skills, with excellent attention to detail.
- Ability to work independently in a fast-paced, dynamic environment.
- Demonstrated ability to coordinate CDMO activities supporting clinical development of pharmaceutical products.
- Ability to thrive in a small-company culture and contribute to creating and implementing processes.
CompensationThe annual base salary range for this position is $105,000.00 to $150,000.00. Individual compensation within this range will be determined based on a variety of factors, including qualifications, skills, relevant experience, job knowledge an location.
In addition to base pay, this role is eligible for a discretionary annual bonus. The Company also offers a comprehensive benefits package, which includes a 401(k) plan, company-sponsored medical, dental, vision, and life insurance, generous paid time off, and a health and wellness program.
Work LocationThe Manager, Clinical Supply Chain role is a remote role based in the US, with occasional travel (up to 20%).
POSITION: Full-Time, Exempt
