AstraZeneca

Global Product Leader- Cell Therapy, Solid Tumor Franchise

AstraZeneca$251K — $377K *
Pharmaceuticals & Biotech
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • Graduate degree (PharmD, PhD, MD, MD/PhD) with 10+ years of relevant experience
  • Experience in strategic design across all development stages with regulatory knowledge
  • Strong understanding of the Oncology therapeutic area and clinical landscapes
  • Proven leadership in a matrixed environment with a track record of driving projects
  • Experience in cultivating internal and external collaborations
  • Success in influencing senior leaders across departments

Responsibilities

  • Lead Cell Therapy Global Product Teams for strategy and execution of development programs
  • Hold accountability for strategy, budget, timeline, and execution of studies
  • Ensure clinical programs support life cycle management and integrated development plans
  • Communicate project development strategy at governance meetings for endorsements
  • Manage risk and adjust strategies based on emerging data
  • Maintain team effectiveness through collaboration and mentoring
  • Develop relationships with external investigators to align projects with clinical care

Benefits

  • Short-term incentive bonus opportunity
  • Eligibility for equity-based long-term incentive program
  • Retirement contribution plan (401(k))
  • Paid vacation and holidays
  • Health benefits including medical, dental, and vision coverage
Full Job Description

The Executive Director, Global Product Leader (GPL 6 Solid Tumor Franchise) - will have overall leadership and accountability for global, cross-functional teams delivering discovery and clinical studies with embedded translational medicine research to establish proof-of-concept data enabling registrational investment strategies. This individual will be accountable for the strategic leadership and execution of clinical development and commercialization plans, aligning prioritization across oncology research units to advance the solid tumor-directed cell therapy pipeline. You will have oncology clinical drug development experience, demonstrated leadership, and be able to critically evaluate the science, clinical data and competitive landscape that underlies each program. You will be able to effectively communicate across a broad range of audiences and have the ability to clearly articulate project-specific strategies and deliverables as it relates to the overall AZ Oncology and Cell Therapy Unit visions.

Typical Accountabilities:

 Leads one or more Cell Therapy Global Product Teams accountable for strategy and execution of development programs to time and quality; current programs include but are not limited to GPC3, STEAP2, and TCR-T cell therapies

 Holds accountability for the strategy, budget, timeline and execution of discovery and/or clinical studies and the generation of supporting data for investment decisions

 Ensures clinical programs support life cycle management strategies, brand strategy plans, and integrated product development plans from AZ99s emerging portfolio

 Leads and communicates the project development strategy at governance meetings to gain endorsement and to secure funding

 Leads the global product team to effectively communicate and manage risk; responsible for monitoring emerging data and for adjusting strategy when necessary

 Responsible for maintaining a high degree of team effectiveness through collaboration, influence, and, as necessary, coaching and mentoring of cross-functional team members

 Maintains relationships with external investigators to ensure projects are consistent with evolving clinical care and experimental approaches

 Responsible for strong partnership with other GPTs, Therapeutic Area leadership teams, and global functional leads across the business

Essential Qualifications:

 Graduate degree such as a PharmD, PhD, MD, or an MD/PhD with 10+ years of relevant experience

 Industry experience in designing strategies through all stages of development, coupled with regulatory knowledge

 Strong knowledge and understanding of the Oncology therapeutic area and evolving clinical landscapes

 Demonstrated experience leading and motivating teams in a highly matrixed environment with a proven track record of entrepreneurial decision-making and driving projects to completion

 Proven record of cultivating and managing internal and external collaborations

 Demonstrated success in communicating with and influencing colleagues and senior leaders in various departments

Desirable Qualifications:

 Experience in development of cell therapies

 Experience in early- and late-stage clinical development programs

 Experience developing data and justification leading to successful Ph3 investment decisions

 Experience in the treatment of and/or development of agents for the treatment of prostate cancer, HCC, or pancreatic cancer

 Experience in due diligence (e.g. asset evaluation, assessment of new biomarker and diagnostic tools)

 Experience in US and/or Global commercialization processes

The annual base pay for this position ranges from $251,610 to $377,415. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours.Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles),to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an at-will position and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

Date Posted

07-Jul-2026

Closing Date

16-Jul-2026

About AstraZeneca

AstraZeneca is a British-Swedish multinational pharmaceutical company that specializes in the research, development, and manufacturing of prescription drugs. The company was formed in 1999 through the merger of Astra AB and Zeneca Group plc. AstraZeneca's products are used to treat a wide range of medical conditions, including cancer, cardiovascular disease, respiratory disease, and diabetes. The company has operations in over 100 countries and employs more than 76,000 people worldwide. AstraZeneca is committed to developing innovative medicines that improve the health and well-being of people around the world.
Learn more about AstraZeneca
Size
83,100 employees
Market Cap
$211.5 billion
Industry
Net Income
$3.1 billion
Founded
1999
5 Year Trend
+10.2%
Revenue
$26.6 billion
NASDAQ

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