AstraZeneca

Global Clinical Head, Respiratory

AstraZeneca$331K — $497K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • MD or equivalent medical degree with specialty training in Respiratory
  • 7 years of experience in respiratory drug development, particularly late-phase
  • Expertise in clinical research related to respiratory diseases
  • Experience leading complex, multinational clinical studies
  • Strong scientific credibility within clinical and regulatory frameworks
  • Proficient in influencing cross-functional teams and geographical regions
  • Experience with benefit/risk assessments and patient management plans
  • Familiar with global regulatory submissions and major regulatory agencies
  • Leadership experience, including mentoring physicians or scientists
  • Solid teamwork capabilities in a global context

Responsibilities

  • Lead all clinical scientific aspects of product development
  • Accountable for clinical deliverables per timelines
  • Provide clinical expertise for strategic project decisions
  • Act as primary contact for clinical matters with TA-Heads and R&D leaders
  • Develop clinical components of regulatory documents and core labeling texts
  • Ensure successful execution of clinical studies and regulatory submissions
  • Collaborate with cross-functional teams on global strategies

Benefits

  • 401(k) retirement plan
  • Paid vacation and holidays
  • Paid leaves
  • Comprehensive health benefits including medical, dental, and vision coverage
  • Incentive bonus opportunities
  • Participation in equity-based long-term incentive program
Full Job Description
The Global Clinical Head (GCH) is the most senior medical scientific expert on an asset/product/indication team and is a core member of the Franchise Team (if applicable) and/or the Global Product Team (GPT).

This role will report to the Vice President Clinical Respiratory.

This person will be accountable for all clinical scientific aspects of the product/asset, including the benefit/risk of a product and/or asset as well as the scientific strategies for clinical components of the Target Product Profile (TPP), Target Product Claim (TPC), Clinical Development Plan (CDP), Clinical components of regulatory documents and core labelling texts.

Provide clinical and medical expertise input into overall project strategy. Will have accountability for the clinical deliverables i.e. clinical studies, clinical components of regulatory submissions etc to time.

Serve as the single point of contact for TA-Heads and R&D leaders for clinical and scientific components of the product and/or indications.

Essential for the Role

  • An MD, or other equivalent medical degree from an accredited university with specialty training in Respiratory or related area.


  • 7 years' relevant experience within the respiratory space, including late-phase drug development experience.


  • Demonstrated deep clinical and research expertise in appropriate disease area


  • Significant hands-on late phase clinical drug development experience.


  • Developed/delivered multiple complex and large studies (e.g., including but not limited to multinational outcome studies).


  • Scientific credibility internally and externally.


  • Demonstrated success in influencing functions outside of clinical and across geographies.


  • Experience of benefit/risk assessment and creating patient risk management plans.


  • Experience of global regulatory submissions and interacting with major regulatory agencies.


  • Demonstrated ability to successfully lead, coach, and mentor other physicians/scientists.


  • Proven teamwork and collaboration skills in a global setting.


  • Credible in scientific and commercial environments.


  • Fit for purpose business acumen, and insight into payer and reimbursement hurdles globally


  • Line management experience.


Desirable for the role

  • Global external awareness within the therapeutic area.


  • Global regulatory awareness.


  • Ability to travel nationally and internationally.


  • Experience in several organizations and geographic locations


  • Experience of working with Market Companies to deliver studies/projects.


  • Experience of clinical/commercial interface.


The annual base salary for this position ranges from $331,873 - $497,810. However, base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program. Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an "at-will position" and the Company reserves the right to modify base salary (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors.

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

Date Posted
07-Jul-2026

Closing Date
30-Jul-2026

About AstraZeneca

AstraZeneca is a British-Swedish multinational pharmaceutical company that specializes in the research, development, and manufacturing of prescription drugs. The company was formed in 1999 through the merger of Astra AB and Zeneca Group plc. AstraZeneca's products are used to treat a wide range of medical conditions, including cancer, cardiovascular disease, respiratory disease, and diabetes. The company has operations in over 100 countries and employs more than 76,000 people worldwide. AstraZeneca is committed to developing innovative medicines that improve the health and well-being of people around the world.
Learn more about AstraZeneca
Size
83,100 employees
Market Cap
$211.5 billion
Industry
Net Income
$3.1 billion
Founded
1999
5 Year Trend
+10.2%
Revenue
$26.6 billion
NASDAQ

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