If you are a current Jazz employee please apply via the Internal Career site

Jazz Pharmaceuticals is undertaking a bold, enterprise-wide transformation to reimagine our operating model and build a patient-centric, agile, and scalable rare disease organization delivering differentiated, precise customer experiences.

This Executive Director, Transformation & Integration Lead is a senior, enterprise leader responsible for setting direction and driving execution of one or more mission-critical transformation programs that shape the future of Jazz. This role operates as a trusted advisor and strategic partner to senior leaders with accountability for designing, orchestrating, and embedding large-scale change across functions.

This is a high-visibility, high-impact role for a leader who operates comfortably at the most senior levels of the organization, influences without authority, and balances strategic vision with hands-on execution. The Transformation Lead will lead integrations for new acquisitions and other business development activities. They will also own complex, multi-year initiatives, navigate ambiguity, and challenge the status quo to deliver measurable, sustainable outcomes.

Key Responsibilities

Enterprise Transformation Strategy & Vision

• Translate Jazz’s enterprise transformation vision into integrated, multi-year strategies, roadmaps, and value cases across assigned functional or enterprise domains

• Partner with fellow Transformation Leads, and senior leaders across Jazz to identify, prioritize, and shape transformation initiatives that drive a high performing organization, growth, patient impact and cost efficiency

• Define future-state operating models considering portfolio evolution, market dynamics, digital enablement, and organizational capabilities

End-to-End Integration and Transformation Leadership

• Serve as accountable executive owner for integrations and key transformation programs, with responsibility for outcomes from concept through full-scale implementation and sustainment

• Lead complex integrations and initiatives spanning multiple workstreams, functions, and geographies, ensuring alignment to enterprise objectives and interdependencies

• Oversee design and implementation of new ways of working, including structure, governance, decision rights, processes, incentives, capabilities, and technology

Executive Partnership & Influence

• Act as a thought partner and challenger to senior leaders, providing objective insight, rigorous analytics, and scenario-based recommendations

• Engage in productive challenge with EC members and functional leaders to drive alignment, resolve trade-offs, and accelerate decision-making

• Represent integration and transformation progress, risks, and outcomes to the Executive Committee and other senior governance forums

Change Leadership & Organizational Adoption

• Set the change agenda and ensure deep, lasting embedding of integration and transformation outcomes across Jazz

• Lead enterprise-wide change management strategies, including stakeholder engagement, communications, capability building, and cultural reinforcement

• Anticipate and actively manage resistance, enabling leaders and teams to adopt new mindsets and behaviors aligned with a customer- and patient-first orientation

Cross-Functional & Matrix Leadership

• Lead and develop matrixed integration andtransformation teams and workstream leaders, fostering accountability, collaboration, and high performance

• Partner closely with executive leaders of assigned functions (e.g., R&D, Commercial, G&A, Digital) to ensure seamless integration and execution of transformation initiatives

• Model enterprise thinking and drive solutions that optimize outcomes for Jazz as a whole, not individual functions

Performance Management & Value Delivery

• Define enterprise-level KPIs, success metrics, and value realization plans linked to integration andtransformation objectives

• Monitor progress rigorously, course correct as needed and ensure delivery of committed outcomes

• Provide transparent, executive-level reporting on milestones, risks, and impact

Qualifications

• Bachelors degree required; advanced degree (MBA, PhD, or equivalent) preferred

• 12+ years of progressive leadership experience in life sciences, healthcare, management consulting, or enterprise transformation roles, working in a team environment

• Proven record of leading integrations in a global pharmaceutical or biotech organizations for both assets in development and commercialized assets

• Experience driving large-scale, complex, cross-functional transformations with measurable business impact; ability to lead cross functional teams

• Demonstrated ability to operate credibly at the Executive Committee level, including preparing and delivering executive-level presentations

• Deep expertise in one or more areas such as Commercial, R&D, G&A, digital transformation, operating model design, or enterprise change

• Strong systems thinker with the ability to connect strategy, data, operating models, and culture

• Highly effective influencer who works across silos and leads through ambiguity without direct authority

• Exceptional analytical, strategic, and problem-solving capabilities.

• Experience with agile, design thinking, lean, or modern change methodologies strongly preferred

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FOR US BASED CANDIDATES ONLY

Jazz Pharmaceuticals, Inc. is committed to fair and equitable compensation practices and we strive to provide employees with total compensation packages that are market competitive. For this role, the full and complete base pay range is:

Individual compensation paid within this range will depend on many factors, including qualifications, skills, relevant experience, job knowledge, and other pertinent factors. The goal is to ensure fair and competitive compensation aligned with the candidates expertise and contributions, within the established pay framework and our Total Compensation philosophy. Internal equity considerations will also influence individual base pay decisions. This range will be reviewed on a regular basis.

At Jazz, your base pay is only one part of your total compensation package. The successful candidate may also be eligible for a discretionary annual cash bonus or incentive compensation (depending on the role), in accordance with the terms of the Companys Global Cash Bonus Plan or Incentive Compensation Plan, as well as discretionary equity grants in accordance with Jazzs Long Term Equity Incentive Plan.

The successful candidate will also be eligible to participate in various benefits offerings, including, but not limited to, medical, dental and vision insurance, 401k retirement savings plan, and flexible paid vacation. For more information on our Benefits offerings please click here: https://careers.jazzpharma.com/benefits.html