AstraZeneca

Executive Director, Radiology & Theranostics 

AstraZeneca$331K — $497K *
Pharmaceuticals & Biotech
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • MD, PhD or equivalent advanced degree in relevant fields such as radiology or oncology
  • 10+ years of leadership experience in pharmaceutical development or imaging sciences
  • Expertise in clinical imaging endpoints and imaging-based biomarkers
  • Strong grasp of oncology drug development across various tumor types
  • Experience leading multidisciplinary scientific teams across geographical boundaries
  • Proven track record of influencing senior stakeholders

Responsibilities

  • Define and execute the global imaging strategy for oncology development
  • Establish a governance model and investment roadmap for imaging capabilities
  • Lead clinical development imaging strategy for pivotal trials
  • Advance imaging-based biomarkers and radiomics initiatives
  • Integrate imaging into early development plans for clinical assets
  • Direct Theranostics and Radioconjugate strategy through Phase III
  • Collaborate with academia and external partners for imaging advancements

Benefits

  • 401(k) retirement plan
  • Paid vacation and holidays
  • Health benefits including medical, dental, and vision coverage
  • Short-term incentive bonus eligibility
  • Equity-based long-term incentive program participation
Full Job Description

Lead an integrated global Radiology & Theranostics organization spanning translational radiology, computational radiology, medical imaging, medical physics, nuclear medicine and translational science. This role will set and execute imaging strategy from preclinical through late clinical development, predominantly in oncology across solid tumors and hematologic malignancies and across therapy modalities, with additional support for trials beyond oncology. Key deliverables include development of imaging-based biomarkers for patient selection, target validation, pharmacodynamic assessment and treatment endpoints.

Location:Gaithersburg MD or Kendall Square MA

Key accountabilities

  • Define and execute the enterprise strategy for Radiology & Theranostics across the oncology portfolio, from preclinical development through late-stage clinical trials.

  • Establish a unified operating model, governance and investment roadmap for global imaging capabilities.

  • Lead imaging strategy for clinical development and pivotal trials, including patient selection, target validation, pharmacodynamic assessment, response assessment, endpoint selection and regulatory alignment.

  • Advance imaging-based biomarkers and radiomics for patient selection, pharmacodynamics, treatment endpoints and biomarker discovery.

  • Earlier, consistent integration of imaging into preclinical, clinical development and indication plans.

  • Lead Theranostics and Radioconjugate imaging strategy from preclinical development through Phase III, including dosimetry and study design.

  • Integrate PET, nuclear medicine, medical physics and translational science capabilities, including external academic collaborations.

  • Ensure imaging strategies are incorporated early into asset and indication plans across solid tumor, hematologic malignancy and selected non-oncology trials.

  • Represent the function in senior governance, business-development evaluations and interactions with regulators and external experts.

  • Recruit, develop and retain a high-performing, multidisciplinary global organization.

Leadership scope

The role is expected to provide strategic oversight across:

  • Translational Radiology: clinical development imaging strategy, radiographic endpoints and imaging-based biomarkers from preclinical through late clinical development

  • Computational Radiology: radiomics, imaging AI and multimodal biomarkers

  • Medical Imaging, Medical Physics & Translational Science:Theranostics, Radioconjugate and dosimetry

  • Regional and external capabilities: including China and EU collaborations 

Measures of success

  • One aligned Radiology & Theranostics strategy and governance model.

  • Earlier, consistent integration of imaging into development plans.

  • Increased use of validated imaging endpoints and biomarkers.

  • Scalable radiomics data and AI infrastructure.

  • StrongTheranostics and Radioconjugate development capabilities.

  • Reduced duplication and improved collaboration across organizational boundaries.

Experience Required

  • MD, PhD or equivalent advanced degree in radiology, nuclear medicine, medical physics, biomedical imaging, oncology or a related discipline.

  • Extensive leadership experience in pharmaceutical development, translational medicine or imaging sciences (minimum of 10+ years of relevant experience).

  • Demonstrated expertise in clinical imaging endpoints, imaging-based biomarkers, radiomics or theranostics, including application to patient selection, target validation, pharmacodynamics and treatment endpoints.

  • Strong understanding of oncology drug development across solid tumors and hematologic malignancies, therapy modalities and global regulatory expectations.

  • Experience leading multidisciplinary, geographically distributed scientific teams.

  • Proven ability to influence senior stakeholders and translate emerging science into portfolio-level strategy.

  • Collaborative, enterprise-minded leader comfortable operating across scientific, clinical, technical and business interfaces.

The annual base pay for this position ranges from $331,873.60 - $497,810.40. Hourly and salaried non-exempt employees will also be paid overtime pay when working qualifying overtime hours. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience.  In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribution (hourly roles), and commission payment eligibility (sales roles). Benefits offered included a qualified retirement program [401(k) plan]; paid vacation and holidays; paid leaves; and, health benefits including medical, prescription drug, dental, and vision coverage in accordance with the terms and conditions of the applicable plans. Additional details of participation in these benefit plans will be provided if an employee receives an offer of employment. If hired, employee will be in an “at-will position” and the Company reserves the right to modify base pay (as well as any other discretionary payment or compensation program) at any time, including for reasons related to individual performance, Company or individual department/team performance, and market factors. 

Date Posted

01-Sep-2026

Closing Date

24-Sep-2026

About AstraZeneca

AstraZeneca is a British-Swedish multinational pharmaceutical company that specializes in the research, development, and manufacturing of prescription drugs. The company was formed in 1999 through the merger of Astra AB and Zeneca Group plc. AstraZeneca's products are used to treat a wide range of medical conditions, including cancer, cardiovascular disease, respiratory disease, and diabetes. The company has operations in over 100 countries and employs more than 76,000 people worldwide. AstraZeneca is committed to developing innovative medicines that improve the health and well-being of people around the world.
Learn more about AstraZeneca
Size
83,100 employees
Market Cap
$211.5 billion
Industry
Net Income
$3.1 billion
Founded
1999
5 Year Trend
+10.2%
Revenue
$26.6 billion
NASDAQ

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