AstraZeneca

Director, US Forecasting & Analytics- Vaccines & Immune Therapies

AstraZeneca$150K — $180K *
Pharmaceuticals & Biotech
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree in a quantitative, scientific, or business-related field required
  • 8+ years' experience in US pharmaceutical commercial forecasting
  • Hands-on model ownership experience across short- and long-term horizons
  • Expertise in scenario-based forecasting and sensitivity analysis
  • Strong integration of multiple data types into decision-grade forecasts
  • Fluency in modern analytics tooling and automation
  • Demonstrated forecast governance and model risk discipline
  • Strong understanding of US market access and payer dynamics

Responsibilities

  • Lead US short-term and long-term demand forecasts for V&I assets
  • Own forecast methodology, assumptions, and governance
  • Integrate primary market research and competitive intelligence into forecast models
  • Identify and quantify key risks and opportunities through scenario analyses
  • Partner with Finance and Marketing for alignment on forecast assumptions
  • Support business planning and governance reviews with executive narratives
  • Serve as a trusted advisor to senior leadership, articulating forecast drivers

Benefits

  • Hybrid work environment averaging three days a week in the office
  • Opportunity to lead a critical role in shaping vaccine and therapy forecasts
  • Engagement with cross-functional teams including Marketing and Finance
  • Potential for continuous improvement and innovation in forecasting processes
  • Professional development through exposure to advanced analytics and AI integration
Full Job Description
Director, US Forecasting & Analytics - Vaccines & Immune Therapies (V&I)

Wilmington, DE

Global Insights, Analytics & Forecasting, BBU

Hybrid Work- on average 3 days a week from office

The Director is a senior commercial insights leader responsible for US demand forecasting and analytics across the Vaccines and Immune Therapies portfolio. The role is predominantly forecast-focused, serving as the US forecasting lead and strategic thought partner to Marketing, Finance, Market Access, and US teams. The position also includes vendor management and forecasting adjacent analytics leadership to ensure the effective deployment of analytical resources and continuous evolution of forecasting and insight capabilities within V&I. Time allocation may vary by business cycle and portfolio priorities.

You'll play a critical role in shaping commercial expectations, risk and opportunity framing, and executive decision-making for in-market and late-stage pipeline vaccines and immune therapies.

What you'll do

US Forecasting Leadership (Core Accountability)
  • Lead US short-term and long-term demand forecasts (TRx, NBRx, volume, patients, revenue) for V&I assets using robust, patient-based and market-based models
  • Own forecast methodology, assumptions, and governance, ensuring objectivity, transparency, and consistency with enterprise standards
  • Integrate primary market research, epidemiology, competitive intelligence, access dynamics, and real-world data into forecast models
  • Proactively identify and quantify key risks and opportunities through scenario and sensitivity analyses
  • Partner closely with Finance, Market Access & Pricing, Marketing, Sales, Medical, and Global Forecasting to ensure alignment on assumptions and implications
  • Support business planning, governance reviews, and opportunity assessments with clear, executive-ready narratives
  • Serve as a trusted advisor to senior marketing and finance leadership, clearly articulating forecast drivers and changes


Analytics & Resource Leadership (Enablement)
  • Provide leadership over forecasting-adjacent analytics, ensuring advanced analytics and insights are embedded into forecasting and business planning
  • Manage and prioritize internal analysts, contractors, and external vendors supporting forecasting and analytics deliverables
  • Partner with data analytics resources, Global IA&F, and GIBEX capability teams to deploy new tools, data sources, and modeling approaches
  • Champion and identify new ways to embed AI and automation into the practice of data analytics and forecasting to drive efficiency, scalability, and decision quality
  • Champion continuous improvement in forecasting processes, AI-enabled modeling, and automation
  • Contribute to the development and sharing of best practices across the V&I forecasting community


Essential for the role

  • Bachelor's degree in a quantitative, scientific, or business-related field (e.g., Statistics, Economics, Mathematics, Engineering, Computer/Data Science)
  • 8+ years' experience in US pharmaceutical commercial forecasting, including in-market and late-stage pipeline assets
  • Hands-on model ownership experience (build, refresh, and performance tracking) across short- and long-term horizons
  • Expertise in scenario-based forecasting, sensitivity analysis, and driver-based narratives to support senior decision making
  • Strong capability integrating multiple data types (e.g., IQVIA, claims, epidemiology, RWD/RWE, primary research) into coherent, decision grade forecasts
  • Knowledge of advanced analytics/ML approaches (e.g., time series, causal inference, ensembles) vs. traditional methods
  • Fluency in modern analytics tooling and automation (e.g., Python/R/SQL, BI/visualization), with ability to partner with data engineering and analytics teams
  • Demonstrated forecast governance and model risk discipline (traceable assumptions, documentation, and clear explanations)
  • Strong understanding of US market access and payer dynamics and how they impact demand (coverage, contracting, channel, policy)
  • Ability to translate complex analysis into clear, executive-ready insights, options, and recommendations
  • Strong commercial competence across key demand levers (positioning, adoption, competitive dynamics, lifecycle events)


Desirable for the role
  • Advanced degree (e.g., MBA, MS, PhD in Statistics, Economics, Decision Sciences, Data Science, or related field).
  • Vaccines and/or Rare Disease experience, including familiarity with immunization dynamics, patient-based forecasting, and lifecycle management in preventive or immune-mediated therapies
  • Change leadership: builds adoption for new tools, processes, and ways of working across cross-functional stakeholders
  • Product perspective for forecasting: defines user needs, success metrics, and a roadmap for portfolio forecasting capabilities
  • Model lifecycle practices (e.g., reproducibility, versioning, monitoring/drift awareness); familiarity with MLOps concepts


Office Working Requirements

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world.

#LI-Hybrid

Date Posted
05-Aug-2026

Closing Date
18-Aug-2026

About AstraZeneca

AstraZeneca is a British-Swedish multinational pharmaceutical company that specializes in the research, development, and manufacturing of prescription drugs. The company was formed in 1999 through the merger of Astra AB and Zeneca Group plc. AstraZeneca's products are used to treat a wide range of medical conditions, including cancer, cardiovascular disease, respiratory disease, and diabetes. The company has operations in over 100 countries and employs more than 76,000 people worldwide. AstraZeneca is committed to developing innovative medicines that improve the health and well-being of people around the world.
Learn more about AstraZeneca
Size
83,100 employees
Market Cap
$211.5 billion
Industry
Net Income
$3.1 billion
Founded
1999
5 Year Trend
+10.2%
Revenue
$26.6 billion
NASDAQ

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