Roche

Director of Functional Genomics

Roche$181K — $337K *
Pharmaceuticals & Biotech
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • PhD in Genetics, Genomics, Molecular Biology, Cell Biology, Computational Biology, or a related field.
  • 10+ years of experience in biotechnology, pharmaceuticals, or advanced research environments.
  • Proven track record of leading high-performance scientific teams.
  • Expertise in functional genomics with familiarity in CRISPR, single-cell or multi-omics, translational profiling, or automation in screening.
  • Exceptional communication skills with experience in navigating complex stakeholder environments.

Responsibilities

  • Define and execute global Functional Genomics strategy for drug development.
  • Advance capabilities in genome-wide screening, perturbation biology, and multi-omics.
  • Collaborate with Research Biology, Computational Sciences, and Translational Medicine to enhance data impact.
  • Integrate emerging technologies like laboratory automation into existing workflows.
  • Mentor and inspire a high-performing team while fostering inclusivity.
  • Build strategic partnerships with academic and industry leaders.

Benefits

  • Relocation benefits available.
Full Job Description
The Opportunity

We believe care should start before disease takes hold. As the Head of Functional Genomics, you will step into a pivotal scientific leadership role within our Translational Genomics and Proteomics (TGP) Center. Leading a world-class, multidisciplinary team, you will shape the scientific strategy and drive the execution of advanced functional genomics capabilities. Your work will directly bridge cutting-edge technology development and biological application to unlock breakthrough insights across our entire therapeutic portfolio.

Key responsibilities include:

  • Drive Scientific Strategy: Define and execute the global Functional Genomics strategy to support target identification, disease biology, biomarker discovery, and drug development priorities.

  • Lead High-Impact Capabilities: Oversee and advance large-scale capabilities in genome-wide screening, perturbation biology, cellular models, sequencing, and multi-omics data generation.

  • Foster Cross-Functional Synergy: Partner closely with Research Biology, Computational Sciences, Translational Medicine, and Development Sciences to turn complex data into meaningful portfolio impact.

  • Champion Technological Innovation: Evaluate, develop, and integrate emerging technologies—including laboratory automation and advanced screening platforms—to solve complex health challenges.

  • Cultivate Top-Tier Talent: Lead, mentor, and inspire a high-performing organization, creating an inclusive and scientifically rigorous environment where individuals thrive and grow.

  • Expand Strategic Collaborations: Establish and nurture external alliances with academic institutions, industry pioneers, and technology partners to keep Roche at the forefront of the industry.


Who You Are

You are a visionary scientific leader who thrives at the intersection of advanced technology and drug discovery. You possess deep scientific curiosity, a collaborative mindset, and a passion for developing people and leading through empowerment.

To be successful in this role, you bring:

  • Advanced Scientific Foundation: A PhD in Genetics, Genomics, Molecular Biology, Cell Biology, Computational Biology, or a closely related scientific discipline.

  • Proven Leadership & Research Experience: 10+ years of progressive experience within biotechnology, pharmaceutical, or advanced research environments, with a track record of leading high-performing scientific teams.

  • Deep Domain Expertise: Robust experience in functional genomics, including hands-on or strategic familiarity with CRISPR-based perturbation, single-cell or multi-omics technologies, translational profiling, or arrayed-based screening automation.

  • Strategic Influence: Exceptional communication and partnership skills, with a demonstrated ability to navigate matrixed environments and build consensus across diverse stakeholders.

  • Innovation Mindset: A strong record of innovation—evidenced by publications, presentations, or technology development—and a passion for translating cutting-edge science into life-changing healthcare solutions.

Relocation benefits are available for this job posting.

The expected salary range for this position based on the primary location of South San Francisco, CA is $181,900 - $337,900.  Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law.  A discretionary annual bonus may be available based on individual and Company performance.  This position also qualifies for the benefits detailed at the link provided below.

About Roche

Roche Holding AG is a Swiss multinational healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, Roche Holding AG, has bearer shares listed on the SIX Swiss Exchange. The company headquarters are located in Basel. Roche is the largest pharmaceutical company in the world, and the leading provider of cancer treatments globally. The company also produces a range of diagnostic tests for medical professionals and patients. Roche was one of the first companies to bring targeted treatments to patients. In 2019, Roche had over 100,000 employees worldwide, and generated revenue of CHF 61.5 billion.
Learn more about Roche
Size
100,920 employees
Industry
NASDAQ

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