AstraZeneca

Commercial Business Director, Advanced Specialty Care, Central Region

AstraZeneca • $233K — $350K *
Pharmaceuticals & Biotech
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's Degree required
  • 8+ years of sales or commercial experience in pharmaceutical or healthcare
  • 5+ years of leadership or people management experience
  • Valid driver's license with a safe driving record

Responsibilities

  • Utilize a comprehensive understanding of disease states and innovative treatments to influence key specialists
  • Leverage analytical insights to optimize account strategies for specialized markets
  • Drive focused account planning and execution to meet business objectives
  • Ensure sales forecasts and operational budgets are achieved regionally
  • Model effective leadership capabilities while building trust with stakeholders
  • Promote a culture of growth and continuous improvement leveraging technology and data
  • Inspire entrepreneurial thinking and patient-centric practices through mentoring and coaching

Benefits

  • Qualified retirement programs
  • Paid time off including vacation and holidays
  • Health, dental, and vision coverage
  • Eligibility for short-term incentive bonuses and equity-based awards
Full Job Description
Commercial Business Director, Advanced Specialty Care, Epithelial Biologics Franchise

As a Commercial Business Director for the Epithelial Biologics Franchise Advanced Specialty Care Team, you'll play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients' lives!

This Commercial Business Director serves as a regional second-line leader for our growing, multi-indication TSLP Franchise, with responsibility for a large organization of District Sales Managers and their sales representatives. The role is accountable for building a high-performance culture, driving competitive business results, and accelerating professional development across the organization while leading the total business within a broad geography spanning independent practitioners, health systems, and alternative sites of care across Pulmonology, Allergy, and Otolaryngology. The Commercial Business Director will establish trusted relationships with key customers and advocates who can influence patient care and advance the business. Key lifecycle priorities include maximizing performance in the established Severe Uncontrolled Asthma (SUA) indication, accelerating growth of the newly launched Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) indication, and preparing the organization for a potential, exciting future launch within the Gastroenterology specialty.

Main Duties and Responsibilities
  • Well-rounded understanding of disease states and treatment pathways and innovative therapies prevalent in Advanced Specialty Care settings and varied healthcare environment, and able to influence specialists and multi-disciplinary stakeholders.
  • Expertise in leveraging analytical objectivity, and complex data and insights to focus on prescribing patterns to optimize account strategies and prioritize high-value accounts for highly specialized markets.
  • Drives a targeted approach in account planning and execution.
  • Demonstrates resilience and adaptative leadership while driving performance in complex and ambiguous Advanced Specialty Care market environment and effective execution of Brand strategies
  • Ensure sales forecasts and operational budgets are met or exceeded within the therapeutic area at a regional level.
  • Model and coach to AZ's Leadership capabilities by creating significant impact, climate of trust and influence over the stakeholders across specialty care environments and external networks.
  • Fosters a Growth Mindset, and continuous learning and improvement. Leverages new technology and data insights to capitalize on opportunities that improves patient care and streamlines process efficiency.
  • Inspires a culture of entrepreneurial thinking and transformative patient-centric practices that embraces curiosity, ownership, accountability and engagement within the entire team through mentoring, coaching and continuous feedforward.


Essential Requirements
  • Bachelor's Degree
  • 8+ yrs of demonstrated Sales or Commercial experience or a combination of: pharmaceutical, healthcare, scientific, clinical, institutional or related industry.
  • 5+ yrs proven leadership capabilities and/or people management experience
  • A valid driver's license and safe driving record


Essential Skills and Capabilities
  • Clinical Acumen
  • Strategic Business Planning
  • Drives Performance & Agility
  • Enterprise Leadership
  • Growth and Innovation Mindset


Desirable Attributes and Experiences
  • Advanced degree in business administration, leadership, or a related field.
  • Specialty healthcare experience, including account management and complex reimbursement models.
  • Track record of competitive performance across the biologics prescription journey in Pulmonology, Allergy, Otolaryngology, and/or Gastroenterology.
  • Broad commercial or leadership experience with demonstrated impact within and beyond the sales function.
  • Proven ability to build culture and followership while developing team business acumen and commercial capabilities.
  • Confident enterprise influencer who constructively challenges, supports, and defends decisions at all organizational levels.
  • Recognized strong collaborator with stakeholders internal and external to the organization.
  • Demonstrated aspiration and potential for broader commercial leadership and organizational impact.


The annual base pay for this position ranges from $ 233,464.00 - 350,196.00 USD. Our positions offer eligibility for various incentives-an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

Date Posted
29-Sept-2026

Closing Date
28-Sept-2026

About AstraZeneca

AstraZeneca is a British-Swedish multinational pharmaceutical company that specializes in the research, development, and manufacturing of prescription drugs. The company was formed in 1999 through the merger of Astra AB and Zeneca Group plc. AstraZeneca's products are used to treat a wide range of medical conditions, including cancer, cardiovascular disease, respiratory disease, and diabetes. The company has operations in over 100 countries and employs more than 76,000 people worldwide. AstraZeneca is committed to developing innovative medicines that improve the health and well-being of people around the world.
Learn more about AstraZeneca
Size
83,100 employees
Market Cap
$211.5 billion
Industry
Net Income
$3.1 billion
Founded
1999
5 Year Trend
+10.2%
Revenue
$26.6 billion
NASDAQ

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