Guidehouse

Bioinformatics Scientist

Guidehouse$95K — $115K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • Master's degree in Bioinformatics or related field.
  • 5+ years of experience in bioinformatics or computational biology.
  • Hands-on experience with next-generation sequencing data.
  • Working knowledge of Genome-Wide Association Studies (GWAS).
  • Background in bulk RNA sequencing analysis.
  • Proficiency in R, Python, MATLAB, Perl, and Unix/Linux scripting.
  • Ability to collaborate with multidisciplinary teams.

Responsibilities

  • Analyze next-generation sequencing and genomic datasets.
  • Interpret biological data to extract meaningful insights.
  • Develop and maintain bioinformatics workflows and analytical tools.
  • Collaborate with research teams to design analytical models and support experiments.
  • Prepare technical documentation and presentation materials.
  • Present findings and conduct bioinformatics training activities.

Benefits

  • Medical, Rx, Dental & Vision Insurance
  • Paid Sick Time & Company Holidays
  • Parental Leave
  • 401(k) Retirement Plan
  • Tuition Reimbursement & Learning Opportunities
  • Employee Assistance Program
  • Corporate Sponsored Community Outreach
Full Job Description
Job Family:
Scientist

Travel Required:
None

Clearance Required:
Ability to Obtain Public Trust

What You Will Do:

We are looking for a Bioinformatics Scientist to support the operational objectives of the National Institute of Environmental Health Sciences (NIEHS) through advanced genomic data analysis, bioinformatics programming, and computational biology support. This position is a full-time position located in Research Triangle Park, NC and is telework eligible.

Analyze NGS, GWAS, genomic, biological, epidemiology, and population-based datasets, including ChIP-Seq, RNA-Seq, miRNA-Seq, SNP/structural variation discovery, imputation, stratification, haplotype, pathway, principal component, meta-analysis, and related statistical analyses.

  • Interpret genomic and targeted population study data, associated metadata, gene expression, exon, tiling, promoter, microarray, and multi-platform results to extract biologically meaningful insights.
  • Develop, implement, deploy, and maintain bioinformatics workflows, custom programs, utility scripts, macros, algorithms, analytical tools, and computational processes supporting experimental design, quality analysis, genome/metagenome integration, and biological discovery.
  • Use commercial software, freeware, custom-developed solutions, and high-performance computing environments to support scientific objectives, maintain workstations, and identify relevant analytical software solutions.
  • Collaborate with biologists, statisticians, bioinformaticians, investigators, and research teams to design analytical models, support data collection and experimental activities, and participate in scientific programming, laboratory, and interdisciplinary meetings.
  • Prepare reports, protocols, technical documentation, publication-quality graphics, and deliverables supporting NGS analyses, GWAS studies, statistical analyses, workflow development, publications, training activities, and scientific presentations.
  • Present findings to investigators, bioinformatics teams, study groups, and external audiences, and develop and deliver bioinformatics training materials, presentations, tutorials, and short-course instruction.


What You Will Need:

  • Master's degree in Bioinformatics, Biostatistics, Computational Biology, Biological Sciences, Mathematics, Computer Science, Environmental Science, Microbiology, Molecular Biology, or related scientific discipline.
  • Minimum of FIVE (5) years of experience in bioinformatics, computational biology, biostatistics, genomics, or a related field.
  • Hands-on background analyzing next-generation sequencing data and genomic datasets.
  • Working knowledge of Genome-Wide Association Studies (GWAS).
  • Background performing bulk RNA sequencing analysis.
  • Skilled in conducting microbiome, phylogenetic, multi-omics, microarray, and cluster analyses.
  • Ability to work with large and complex biological datasets.
  • Proven ability to develop bioinformatics pipelines and analytical workflows.
  • Proficiency with R, Python, MATLAB, Perl, Shell scripting, Unix/Linux environments, and Java.
  • Demonstrated ability to collaborate with multidisciplinary scientific teams.
  • Ability to prepare technical reports, scientific documentation, and publication-quality visualizations.
  • Must be able to obtain and maintain a Federal or DoD "public trust"; candidates must receive approved adjudication prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferred.


What Would Be Nice To Have:

  • Ph.D. in Bioinformatics, Biostatistics, Computational Biology, Biological Sciences, or a related scientific discipline.
  • Background supporting federal biomedical or environmental health research programs.
  • Strong written and verbal communication skills, including presentation experience.
  • Ability to develop custom bioinformatics applications and advanced computational algorithms.
  • Familiarity supporting high-performance computing environments.
  • Ability to provide bioinformatics training, mentoring, and instructional support.
  • Demonstrated contributions to scientific manuscripts and peer-reviewed publications.
  • Collaboration across interdisciplinary genomic, epidemiologic, and population-based research programs.


What We Offer:

Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.

Benefits include:
  • Medical, Rx, Dental & Vision Insurance
  • Personal and Family Sick Time & Company Paid Holidays
  • Parental Leave
  • 401(k) Retirement Plan
  • Group Term Life and Travel Assistance
  • Voluntary Life and AD&D Insurance
  • Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts
  • Transit and Parking Commuter Benefits
  • Short-Term & Long-Term Disability
  • Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities
  • Employee Referral Program
  • Corporate Sponsored Events & Community Outreach
  • Care.com annual membership
  • Employee Assistance Program
  • Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)
  • Position may be eligible for a discretionary variable incentive bonus


About Guidehouse

Guidehouse is a management consulting firm headquartered in Washington, D.C. The firm provides consulting services to clients in the public and commercial sectors, with a focus on energy, financial services, healthcare, national security, and aerospace and defense. Guidehouse was founded in 2018 as a spin-off from PwC. The firm has over 7,000 employees and operates in more than 50 locations worldwide.
Learn more about Guidehouse
Size
8,000 employees
Industry
Founded
2018

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