Regeneron Pharmaceuticals, Inc

Associate Scientist - Therapeutic Proteins - Antibody Radioconjugates Technology

Regeneron Pharmaceuticals, Inc • $70K — $110K *
Tarrytown, NY 10591In-Person
Pharmaceuticals & Biotech
Less than 5 years of experience
Today
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Job Overview by Ladders

Qualifications

  • B.S. in Chemistry, Biochemistry, Chemical Engineering, Chemical Biology, or a related field with 1-2 years of lab experience.
  • Comfortable working with radioactive materials; completion of radiation safety training is required.
  • Hands-on experience with protein chemistry and bioconjugation techniques; open to learning.
  • Experience with chromatographic techniques and mammalian cell culture proficiency.
  • Proficient in data analysis software and electronic lab notebook systems.
  • Ability to lift 50 lbs.

Responsibilities

  • Perform bioconjugation of antibodies with bifunctional chelating agents and fluorescent probes as per validated protocols.
  • Characterize antibody bioconjugates using SE-HPLC, SDS-PAGE, Western blot, and UV/Vis spectroscopy.
  • Radiolabel bioconjugated antibodies with Zr-89, Cu-64, or other radionuclides; purify products for imaging studies.
  • Conduct quality control testing using radio-HPLC, radio-iTLC, and gamma counting for tracer quality verification.
  • Maintain mammalian cell culture lines and execute cell-based assays to assess tracer functionality.
  • Coordinate tracer preparation timelines with imaging scientists and project teams across therapeutic areas.
  • Maintain detailed electronic lab notebooks and radiation safety records in line with regulations.

Benefits

  • Opportunity to contribute to the development of life-changing medicines.
  • Work in a collaborative and fast-paced environment.
  • Engagement in advanced imaging techniques for preclinical studies.
  • Direct involvement in cancer and immuno-oncology research.
  • Opportunity to develop skills in radiochemistry and bioconjugation.
Full Job Description

Build our future together:


At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a highly motivated, detail-oriented, and dependable Associate Scientist to join Therapeutic Proteins - Antibody Radioconjugates Technology, conjugating antibodies with bifunctional chelates and fluorescent probes, and radiolabeling conjugated antibodies to support preclinical immunoPET (iPET) and Cryo-fluorescence Tomography (CFT) imaging. You'll generate and characterize Zr-89 radiolabeled and fluorescently-conjugated tracers from our portfolio of antibodies and antibody-based therapeutics, enabling quantitative in vivo imaging studies across Oncology, Immuno-Oncology, and other therapeutic focus areas. Your work will directly enable same-day imaging studies that visualize biodistribution, tumor/tissue targeting, and pharmacokinetics of therapeutic candidates in preclinical models.

When & where:
Location: Tarrytown, NY - On-site

Discover your role:

  • Performs bioconjugation of antibodies with bifunctional chelating agents (DFO, DOTA, etc.) and fluorescent probes following validated protocols
  • Characterizes antibody bioconjugates using SE-HPLC, SDS-PAGE, Western blot, and UV/Vis spectroscopy
  • Radiolabels bioconjugated antibodies with Zr-89, Cu-64, or other radionuclide isotopes; purifies radiolabeled products for same-day use in time-critical imaging studies
  • Runs quality control testing using radio-HPLC, radio-iTLC, and gamma counting to verify tracer quality before release
  • Maintains mammalian cell culture lines and performs cell-based assays to validate tracer binding and function
  • Coordinates tracer preparation timelines with imaging scientists and project teams across multiple therapeutic areas
  • Maintains detailed electronic laboratory notebooks and radiation safety records in compliance with regulations
  • Maintains instruments, troubleshoots instrumental/experimental problems, and orders/maintains supplies

This job might be for you if you:

  • Have hands-on experience with protein chemistry, bioconjugation, and chromatographic techniques; experience performing radiochemistry is a plus
  • Thrive in a collaborative, fast-paced environment where reliability and punctuality directly impact team success
  • Take pride in maintaining accurate, complete laboratory records
  • Excel at attention to detail and following established protocols with precision
  • Are self-motivated and eager to work independently after training
  • Have strong communication skills

This role requires:

  • B.S. in Chemistry, Biochemistry, Chemical Engineering, Chemical Biology, or a related field with 1-2 years of laboratory experience
  • Comfort working with radioactive materials and willingness to complete radiation safety training
  • Hands-on experience with protein chemistry and bioconjugation techniques, or strong foundational knowledge with willingness to learn
  • Experience with chromatographic techniques (HPLC, FPLC, or column chromatography) and mammalian cell culture
  • Proficiency with computers, data analysis software (Excel, Prism, or similar), and electronic laboratory notebook systems
  • Ability to lift 50 lbs

Salary Range (annually)

$70,300.00 - $110,100.00

About Regeneron Pharmaceuticals, Inc

Regeneron Pharmaceuticals is a biopharmaceutical company that discovers, develops, and commercializes pharmaceutical products for the treatment of serious medical conditions. The Company has therapeutic candidates in clinical trials for the potential treatment of cancer, eye diseases, and inflammatory diseases, and has preclinical programs in other diseases and disorders. The company’s product portfolio includes EYLEA, an aflibercept injection; ARCALYST, a rilonacept Injection for subcutaneous use; ZALTRAP for metastatic colorectal cancer; trap fusion proteins; and fully human monoclonal antibodies. On March 26, 2012, it was announced that Sanofi and Regeneron are in development with a new cholesterol drug which will help reduce cholesterol up to 72%. Regeneron Pharmaceuticals was founded in 1988 and is currently headquartered in New York, USA.

Regeneron Pharmaceuticals, Inc Careers

Join the innovative team at Regeneron Pharmaceuticals, Inc, a leading biotechnology company renowned for its commitment to science-driven solutions. This is an unparalleled opportunity to advance your career with a company at the forefront of medical breakthroughs and clinical research.

Work You’ll Do

At Regeneron Pharmaceuticals, Inc, you will collaborate with some of the brightest minds in the industry, engaging in work that directly contributes to the health and well-being of populations globally. Our diverse team of professionals is dedicated to pioneering developments in biotechnology through continuous innovation and rigorous research.

Explore Job Opportunities and Growth

Regeneron offers a variety of job opportunities that encourage professional growth and personal achievement. Whether you're seeking an entry-level position or a more senior role, you will find a path that aligns with your career ambitions and skills. Our supportive culture emphasizes leadership development and diversity training, ensuring every team member can thrive.

Internship Programs

Kickstart your career with a Regeneron internship. Our programs provide invaluable industry experience, mentoring from seasoned professionals, and opportunities to develop skills that are crucial in the biotech field. Interns at Regeneron gain hands-on experience, contributing to projects that matter.

Benefits and Culture

Choosing to work at Regeneron Pharmaceuticals, Inc means choosing a career that comes with competitive benefits designed to support you both professionally and personally. We offer comprehensive health benefits, retirement plans, and wellness programs. Our inclusive culture fosters an environment where every employee can flourish, driven by collaboration and mutual respect.

Innovation and Leadership

Lead the way in biotechnological innovation with Regeneron. Our leadership is constantly looking towards the future, investing in cutting-edge technology and research that pave the way for medical advancements. At Regeneron, leadership and innovation go hand in hand, creating a dynamic where breakthroughs are common.

Networking and Professional Development

Enhance your professional network and skill set through Regeneron’s extensive networking opportunities and ongoing professional development programs. We believe in nurturing our talent with advanced training sessions and regular workshops that cover the latest trends and technologies in the biotech industry.

Join Our Team

Discover the impact you can make in a career at Regeneron Pharmaceuticals, Inc. Search for open positions that match your skills and interests. We are continuously hiring and looking for passionate, curious, and innovative team players.

Stay Connected

Keep up to date with the latest at Regeneron by following our careers blog. Gain insights from the experts and learn more about the exciting world of biotech at Regeneron Pharmaceuticals, Inc.

Prepare for Your Interview

Ready to join us? Prepare your resume and refine your interview skills to become part of a company that’s dedicated to changing lives. Personalize your job search and get tailored job alerts directly to your inbox, so you never miss an opportunity to be part of our team. At Regeneron Pharmaceuticals, Inc, your career is poised for tremendous growth and innovation. Explore the opportunities today and be part of a team that’s shaping the future of biotechnology.
Learn more about Regeneron Pharmaceuticals, Inc
Size
10,368 employees
Market Cap
$78.1 billion
Industry
Pharmaceuticals & Biotech
Net Income
$3.5 billion
Founded
1988
5 Year Trend
+27%
Revenue
$8.4 billion
NASDAQ
REGN
* Ladders Estimates

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