AstraZeneca

Associate Director, Cell Therapy Supply Chain Ops Transformation & Performance Lead

AstraZeneca$121K — $181K *
Pharmaceuticals & Biotech
8 - 10 years of experience
Job Overview by Ladders

Qualifications

  • Bachelor's degree in Supply Chain, Engineering, Operations, Life Sciences, Business, or related field.
  • 8+ years of relevant experience with a Bachelor's degree, or 6+ years with a Master's degree or MBA.
  • Experience in biopharmaceutical, biotech, advanced therapy, or regulated environments.
  • Strong understanding of supply chain processes like planning, procurement, and logistics.
  • Lean Six Sigma Green Belt required.
  • Proven experience in leading business process transformation initiatives.
  • Strong facilitation and stakeholder management skills.

Responsibilities

  • Lead strategic transformation initiatives for supply chain scalability and performance.
  • Establish end-to-end supply chain process frameworks for governance and continuous improvement.
  • Partner with leaders to design and implement scalable operating models.
  • Drive operational excellence with Lean methodologies and process simplification.
  • Facilitate workshops to assess processes and develop implementation roadmaps.
  • Enhance the global supply chain performance management framework and KPIs.
  • Develop metrics and reporting structures for performance visibility.

Benefits

  • Qualified retirement programs.
  • Paid time off including vacation and holidays.
  • Health, dental, and vision coverage.
Full Job Description
The Associate Director, Cell Therapy Supply Chain Operations Transformation & Performance Lead is responsible for driving business process transformation, operational excellence, and performance management across the Cell Therapy Global Supply Chain organization. Reporting to the Director, Strategy & Business Planning, this role partners with supply chain leaders and business process owners to simplify, standardize, and scale end-to-end supply chain processes while strengthening governance, performance visibility, and decision-making.

This role will be instrumental in enabling AstraZeneca's bold cell therapy ambitions by helping build a scalable, future-ready supply chain operating model that can support the rapid growth and evolving complexity of the business. The leader will help shape the next generation of cell therapy supply chain capabilities through Lean principles, process transformation, and digitization.

This is an opportunity to play a key role in transforming how the Global Supply Chain organization operates, scales, and delivers - enabling sustainable growth while strengthening operational excellence, agility, and end-to-end performance.
Key Responsibilities
  • Lead strategic transformation initiatives that enable AstraZeneca's bold cell therapy ambitions and improve supply chain scalability, transparency, agility, and execution.
  • Establish and maintain the end-to-end supply chain process framework, including standards, governance, ownership, process architecture, and continuous improvement.
  • Partner with supply chain leaders and cross-functional business process owners to design and implement future-state, scalable operating models.
  • Drive operational excellence through Lean methodologies, structured problem-solving, process simplification, standardization, and continuous improvement.
  • Facilitate cross-functional workshops to assess current-state processes, identify opportunities, define future-state solutions, and develop implementation roadmaps.
  • Develop and enhance the global supply chain performance management framework, including KPIs, Tier-based performance management, management review routines, and escalation processes.
  • Establish meaningful metrics, data definitions, and reporting structures that improve performance visibility, accountability, and data-driven decision-making.
  • Support governance forums and cross-functional management routines that strengthen alignment, prioritization, decision-making, and issue resolution.
  • Partner with Digital and Supply Chain teams to identify and implement automation, advanced analytics, digital, and AI-enabled solutions that enhance supply chain effectiveness.
  • Leverage data and analytics to identify trends, uncover improvement opportunities, measure transformation outcomes, and support strategic decision-making.
  • Build strong partnerships across Planning, Procurement, Manufacturing, Logistics, Quality, Digital, and other key functions to drive end-to-end transformation.
  • Lead change management and stakeholder engagement to drive adoption of new processes, tools, operating models, and governance structures.
  • Develop and communicate transformation roadmaps, progress, performance insights, and key outcomes to senior stakeholders.
  • Identify opportunities to simplify, standardize, and scale supply chain capabilities as the cell therapy business continues to evolve.
  • Help establish a culture of continuous improvement, innovation, accountability, and operational excellence across the Global Supply Chain organization.
Qualifications

Required
  • Bachelor's degree in Supply Chain, Engineering, Operations, Life Sciences, Business, or related field.
  • 8+ years of relevant experience with a Bachelor's degree, or 6+ years with a Master's degree or MBA.
  • Experience in biopharmaceutical, biotech, advanced therapy, or other highly regulated operations environments.
  • Strong understanding of end-to-end supply chain processes, including planning, procurement, manufacturing, logistics, inventory management, and performance management.
  • Lean Six Sigma Green Belt required.
  • Proven experience leading business process transformation, operational excellence, or operating model transformation initiatives.
  • Experience establishing governance structures, KPIs, management routines, and performance frameworks.
  • Demonstrated ability to translate complex business challenges into scalable, practical solutions.
  • Strong facilitation, stakeholder management, influencing, and change leadership skills.
  • Strong analytical and problem-solving capabilities with a data-driven mindset.
  • Ability to operate effectively in a complex, cross-functional environment and influence stakeholders without direct authority.

Preferred
  • Experience in cell therapy, gene therapy, or advanced therapy supply chain environments.
  • Experience supporting or leading transformation within a rapidly growing or evolving business.
  • Experience leading large-scale transformation programs across cross-functional organizations.
  • Experience with automation, advanced analytics, process mining, digital technologies, or AI-enabled supply chain solutions.
  • Lean Six Sigma Black Belt preferred.
  • Additional certifications such as Prosci, PMP, Scrum Master, CSCP, or CPIM.
  • MBA or advanced degree in a related discipline.

The annual base pay for this position ranges from $121,149.60 - $181,724.40. Our positions offer eligibility for various incentives-an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

Date Posted
12-Aug-2026

Closing Date
30-Aug-2026

About AstraZeneca

AstraZeneca is a British-Swedish multinational pharmaceutical company that specializes in the research, development, and manufacturing of prescription drugs. The company was formed in 1999 through the merger of Astra AB and Zeneca Group plc. AstraZeneca's products are used to treat a wide range of medical conditions, including cancer, cardiovascular disease, respiratory disease, and diabetes. The company has operations in over 100 countries and employs more than 76,000 people worldwide. AstraZeneca is committed to developing innovative medicines that improve the health and well-being of people around the world.
Learn more about AstraZeneca
Size
83,100 employees
Market Cap
$211.5 billion
Industry
Net Income
$3.1 billion
Founded
1999
5 Year Trend
+10.2%
Revenue
$26.6 billion
NASDAQ

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