Position Summary
TerraPower Isotopes is seeking an Analytical Radiochemist to support the analytical characterization, quality control testing, and release of radioisotopes and radiopharmaceutical precursors produced at the Everett facility.
This role is central to ensuring the analytical reliability and regulatory compliance of isotope production operations. The Analytical Radiochemist will contribute to the development, validation, transfer, and execution of analytical methods supporting both process characterization and GMP manufacturing.
The successful candidate will work within a multidisciplinary team of scientists, engineers, and quality professionals to generate high-quality analytical data that enables safe production, regulatory compliance, and timely product release.
This position is well suited for analytical scientists who enjoy solving complex measurement challenges, improving analytical robustness, and operating in a mission-driven environment where rigorous science directly supports medical innovation.
Key Responsibilities• Perform analytical testing supporting in-process monitoring, stability studies, and final product batch release.
• Develop, optimize, and execute analytical methods for radioisotopes and radiopharmaceutical precursors.
• Participate in method validation, qualification, transfer, and verification activities following ICH Q2 and USP guidance.
• Operate analytical techniques including gamma spectroscopy, alpha spectroscopy, ICP-MS/ICP-QQQ-MS, ICP-OES, radio TLC scanning, and liquid scintillation counting.
• Perform radioactivity calculations including decay corrections and isotopic equilibrium assessments.
• Calibrate and troubleshoot instrumentation such as HPGe detectors, ICP-MS/OES, alpha spectroscopy systems, and LSC systems.
• Generate and review analytical data according to ALCOA+ data integrity principles.
• Utilize a LIMS compliant with 21 CFR Part 11 to manage analytical data and laboratory records.
• Support investigations including OOS, OOT, and laboratory deviations.
• Contribute to root cause analysis and CAPA implementation.
• Author and maintain SOPs, analytical methods, validation documents, investigation reports, and other laboratory documentation supporting radioisotope production.
• Develop and implement analytical procedures, documentation, and laboratory forms relevant to isotope production and quality control activities.
• Prepare analytical standards, reagents, and reference materials.
• Conduct laboratory work within radiological controlled areas and glovebox environments.
• Collaborate with QA, Manufacturing, Radiochemistry, and Engineering teams.
• Identify opportunities to improve analytical reliability and laboratory efficiency.
• Support training and mentoring of laboratory staff.
• Support management of laboratory chemical inventories, including ordering, evaluation of storage conditions, labeling, and compliant disposal of chemicals.
• Maintain organized and safe laboratory environments, including analytical laboratories and radiological controlled areas.
• Support, maintain, or lead integration of analytical instrument reporting capabilities with the Laboratory Information Management System (LIMS).
Required Qualifications• Bachelor's degree or higher in Chemistry, Radiochemistry, or related scientific discipline.
• 3+ years of hands-on experience performing analytical or radioanalytical measurements.
• Experience with wet chemistry and analytical sample preparation.
• Experience operating, calibrating, or troubleshooting analytical instrumentation.
• Experience developing and implementing analytical procedures, documentation, and laboratory records relevant to analytical testing or isotope production.
• Demonstrated ability to independently plan, design, execute, and analyze complex experiments and analytical activities while meeting project or production timelines.
• Ability to work in a regulated laboratory environment supporting pharmaceutical or radiopharmaceutical production.
Preferred Qualifications• Experience with analytical method development, validation, qualification, or transfer.
• Experience in laboratories operating under cGMP (21 CFR 210/211) or GLP.
• Familiarity with radiochemical analysis and isotope characterization.
• Experience working in radiological laboratories or glovebox environments.
• Experience using laboratory information management systems (LIMS) compliant with 21 CFR Part 11.
• Experience using laboratory quality support software or electronic systems for data management and records retention.
• Ability to interpret regulatory requirements, codes, and standards and incorporate them into laboratory procedures and documentation.
Key CompetenciesScientific Rigor and Attention to Detail
• Meticulous approach to testing, calculations, and documentation.
Problem Solving and Analytical Thinking
• Ability to investigate analytical issues and determine root causes.
Technical Communication
• Strong technical writing and communication skills.
Operational Discipline
• Ability to work in fast-paced production environments while maintaining data quality.
• Flexibility to work periodic off-shift hours in support of routine production and product quality control activities.
Team Collaboration
• Demonstrates respect for colleagues, integrity in scientific work, and open communication to support a positive and collaborative work environment.
Job Functions:Job Functions are physical actions and/or working conditions associated with the position. These functions may also constitute essential functions for the job which the employee must be able to fulfill, with or without accommodation. Information provided below is to help describe the job so that the applicant has a reasonable understanding of the job duties/expectations. An applicant's ability to perform and/or tolerate these actions and conditions will be discussed and workplace accommodations may be made on a case-by-case basis following an individualized assessment of the applicant and other considerations, including but not limited to any governing safety standards.
- Motor Abilities: Sitting for extended periods, bending/stooping, grasping/gripping, fine motor control (hands)
- Physical exertion and/or requirements: Minimal, with ability to safely lift up to 25 pounds.
- Repetitive work: Prolonged
- Special Senses: Visual and audio focused work
- Work Conditions: Stairs, typing/keyboard, standard and/or sitting working environment of >8 hours/day
- Travel required 0-10%
TerraPower Isotopes' technology is controlled for export by various agencies of the U.S. Government. TerraPower Isotopes must evaluate applicants who are foreign nationals (other than asylees, refugees, or lawful permanent residents) in accordance with U.S. Government export control requirements. To facilitate TerraPower's export control reviews, you will be asked as part of the application process to identify whether you are a U.S. Citizen or national, asylee, refugee, or lawful permanent resident of the United States. Government export authorization approval times vary. Based on the business needs for a particular position, TerraPower Isotopes may not consider a foreign national from a country if it is impracticable to obtain timely Government export approval.
Job details Job Type: Full-time
$102,804 - $154,206
*We typically place offers in the lower to middle portion of the range to maintain internal equity and allow room for growth. Any salary offered within the posted salary band is based on market data and commensurate with the selected individual's qualifications experience. This range is specific to Washington State.
Benefits:- Competitive Compensation
- Salary, eligible to participate in discretionary short-term incentive payments
- Comprehensive Medical and Wellness Benefits
- Medical
- Vision
- Dental
- Life and Disability
- Gender Affirmation Benefits
- Parental Leave
- 401k Plan
- Generous Paid Time Off (PTO)
- 21 days of annually accrued PTO
- Generous Holiday Schedule
- Relocation Assistance
- Professional and Educational Support Opportunities
TerraPower Career and Benefits information: https://www.terrapower.com/careers/
