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The core responsibility of the successful candidate will be to drive the development of innovative solutions to complex chemistry problems across a diverse portfolio of projects in the discovery phase...
Design and execute the automated high throughput solid-phase synthesis, purification and analysis of novel oligonucleotides with various chemical modifications and scales using modern synthesis platfo...
Serve as a scientific expert in parallel medicinal chemistry with both internal and external partners and provide recommendations regarding new targets, new synthetic strategies and emerging external...
Applying a variety of informatics and modeling techniques to accelerate the evolution of drug discovery leads to drug candidates.
Overseeing environmental fate and metabolism studies at external laboratories to assess product safety including protocol preparation, interaction with lab scientists, critical evaluation of data, pro...
This position will work closely with colleagues in chemistry, screening and target biology and other groups to expand our understanding of ADAR biology and biochemistry...
Strong track record in applying modern synthetic organic techniques to advance small-molecule drug discovery programs, include a strong publication/patent record...
The preferred candidate will be comfortable balancing the use traditional approaches, exploring novelty on the cutting edge of modern small-molecule drug discovery, and have a thirst to constantly lea...
Facilitate the design of new residue selective linkers by interacting with other chemists and interdisciplinary team members to optimize DMPK, in vitro, and in vivo pharmacology properties...
Support the development of analytical assays for biochemical and biophysical characterization of AAV, Cas9, guide RNAs and gene edited cells.