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Integrate data from large human genetic datasets, including Genome-Wide Association Study (GWAS), RVAS, eQTL/pQTL studies, and Mendelian genetics, to identify potential therapeutic targets across Card...
Lead a matrixed team in the acquisition and interpretation of MS/MS data, particularly fragmentation patterns, to identify and characterize complex natural products expressed by fungi...
Evaluate new targets, using proprietary and public data sources, to synthesize a coherent and rigorous view of the pros and cons of each across many dimensions...
Perform research centered around DNA repair with the aims of developing next-generation gene editing strategies using based gene editing tools.
Develop novel test methods and/or adapt, when available, test methods from standards, compendia and literature using best practices for physical and chemical characterization of materials and drugs...
We are looking for a self-motivated scientist with a strong background in Protein Biochemistry to join our Biomolecular Discovery team. We are applying state of the art technology towards the discover...
Provide medicinal chemistry expertise to drive programs from hit generation to clinical candidate selection using state of the art design principles and strategies. Work collaboratively across scienti...
Experience with cheminformatics analyses such as nearest neighbor searches, R-Group deconvolution, screening informatics. Ability to perform complex data integration, analysis, and visualization to dr...
Communicate unambiguous critical and significant project information to various bodies including project teams and leadership as required.
Develops protocols and informed consent documents for clinical studies. Monitors, & reviews along with the medical monitor safety and efficacy data in ongoing studies; monitors GCP compliance with hel...
Generate, manage, evaluate, and maintain critical data in a highly organized manner, providing statistical analysis and troubleshooting where appropriate...
Develop processes and scale-up for consistent manufacture of quality materials for GMP clinical/commercial supply. Refine scale-down models for process characterization and optimization...
Oversee design, development, validation, and implementation of translational and clinical-grade assays to answer essential research questions supporting clinical programs. Perform technical assessment...