Principal Scientist Jobs Near Burlington, MA

Help lead strategy and planning of early-stage research programs, including identifying, evaluating, and championing new ideas and technologies.

Establish effective working relationships within Jounce functions, including Research, Regulatory, Quality Assurance and Legal departments

Manages formulation development and clinical manufacturing activities at external laboratories and manufacturing facilities.

Data Science team that combines areas of expertise to gain a molecular understanding of disease etiology, to identify novel targets and chemical matter, assess preclinical model translation relevance...

Design, synthesize, and characterize novel molecules targeting diverse protein targets. Apply structure-based drug design and computational and modeling approaches to prioritize syntheses...

Serve as the In Vivo Pharmacology Lead on project teams, setting the strategy for in vivo model selection, study design/endpoints, and data intrepretation...

Collaborate with bench scientists to identify key questions that can be addressed via genomics, partner in experiment design, and execute targeted computational analysis plans...

Ability to independently solve problems, to think critically and creatively as part of a fast-paced and multidisciplinary team.

Use a broad array of DMPK data to enable integrated analyses of biopharmaceutics, drug metabolism, PK/PD, human PK/dose projections and DDI risk.

Providing scientific leadership in ML/AI for Chemistry and provide recommendations on emerging technologies and capabilities.

In partnership with functional/project leaders, set the toxicology strategy and plans for Black Diamond’s programs in late discovery and development; be the functional area representative for nonclini...

Drive medicinal chemistry efforts in drug discovery and technology projects, designing high quality small molecules to enable and progress projects, first as proof-of concept and then to candidate sel...

Work with cross-functional program teams providing budgets, updates, and project management support required to achieve pre-clinical and clinical development goals and timelines...

Work with multidisciplinary preclinical development teams to enable the transition from hit to lead candidate as well as final nomination of a clinical candidate...

Demonstrating strategic thinking for project delivery, identification and implementation of the next disruptive technology within UCB in order to stay at the forefront of drug discovery...

Proposes new product concepts and ideas; prepares design concepts and assists in building the initial prototype products.

Develop solutions for enzymatic reactions and chromatography that produce high quality preclinical test agents with high throughput. Prepare reports and presentations that support process improvements...

Develop and apply concepts crossing multiple fields including computer vision, machine learning, signal processing, and state estimation; you will work in tightly-knit, project-oriented teams with a P...

Maintain broad knowledge of biochemical mechanisms of program targets and as well as stay current in advances in biochemistry and enzymology methodologies, techniques and technologies...

Develop, validate, and implement LC-MS analytical assays to develop a mechanistic understanding of transporter biology and to support the discovery small molecules and biologics for modulation of tran...

Serve as the scientific and compliance monitor for bioanalytical studies outsourced for supporting preclinical developmental and translational research. Anticipate and mitigate potential technical an...

Lead the department by keeping up with current methodology and technology for protein purification and downstream processes to train and develop the team...

Manage a small team of internal scientists and develop close working relationships with a network of CROs and academic labs to deliver high-quality in vivo pharmacology data...

The ideal candidates will be responsible for attracting and developing clients and providing consulting services in the areas of environmental, ecological, and air sciences practice areas. These indiv...

Provide clinical input to support claims and statements for new product development, post market surveillance, recertification, and business development...