We are currently expanding the molecular modality focus at our San Diego research site (FRI) to include small molecules in search of novel therapeutics in key disease areas of interest. The Molecular Design department is seeking an experienced small molecule medicinal chemist to provide scientific leadership as Ferring embraces this modality for select targets. This is a great opportunity to influence the future of small molecule research at FRI and simultaneously help discover NMEs / clinical candidates.
Roles and Responsibilities
- Provide scientific leadership, from a medicinal chemistry perspective, to help shape the future of small molecule research at FRI
- Lead either internal and/or external small molecule discovery projects to help achieve departmental and site-wide milestones and goals
- Provide expert insight into small molecule designs and design strategy
- Provide synthetic organic expertise to enable novel synthetic routes to novel molecules of interest
- Collaborate with and manage external partners and CROs to lead small molecule project(s) towards clinical candidate selection
- Identify optimal work flows balancing internal and external resources to achieve medicinal chemistry goals as efficiently as possible
- Network and collaborate with other departments within FRI and with other Ferring sites to integrate small molecule discovery
- Present recent work at departmental, governance and site-wide meetings
- Future potential to supervise FRI scientists as the department grows
- Ph.D. in synthetic organic chemistry or medicinal chemistry.
- 10+ years of experience in the pharmaceutical / biopharmaceutical industry as a medicinal chemistry leader driving multiple small molecule discovery programs to successful milestones and candidate selection(s). Experience with computational approaches and tools is highly preferable.
- Deep knowledge of screening approaches towards the identification of novel small molecule hits and leads.
- Experience in directing and managing synthetic work at various CROs.
- Strong knowledge of preclinical ADME assays to help prioritize hit and lead selection along the medicinal chemistry path to candidate selection.
- Outstanding communication skills with the ability to seamlessly network across disciplines within FRI as a true team player.