Sr. Principal Scientist - Lung Diseases in Ridgefield, CT

$100K - $150K(Ladders Estimates)

Boehringer Ingelheim Pharmaceuticals, Inc   •  

Ridgefield, CT 06877

Industry: Pharmaceuticals & Biotech


8 - 10 years

Posted 65 days ago

This job is no longer available.


The Sr. Principal Scientist is primarily responsible for performing and managing scientific and technical activities, which may also include responsibility for the management of scientific staff. Proficient or develop expertise in Pulmonary Fibrosis-Interstitial Lung Diseases and expand knowledge on other immunology and respiratory research areas by keeping abreast of relevant literature. Candidate must have strong analytical and problem-solving skills with proven track record of high research accountability and productivity both independently with minimal supervision and within a team setting in a matrix environment.

Lead scientific concepts and projects in the area of Pulmonary Fibrosis-Interstitial Lung Diseases to generate data that helps drive highly differentiated disease positioning concepts. Work with Biomarker and Translational systems groups to collaboratively establish and implement data packages that will help teams deliver on early concepts for patient stratification. Establish and maintain external collaborations to utilize patient samples for developing disease linkages and to strengthen value proposition of drug concepts. Manage and prioritize multiple projects within the laboratory and interface with DCD, exploratory innovation group and in vivo groups. As appropriate, serve as the biology Research Project Leader on portfolio projects. Define, implement and communicate tactics for achieving overall R&D project goals. Mentor junior staff for effective planning and conduct of laboratory experiments and thorough evaluation and interpretation of data. Responsible for the management and development of scientific staff.

As an employee of Boehringer Ingelheim, you will actively contribute to the discovery, development and delivery of our products to our patients and customers. Our global presence provides opportunity for all employees to collaborate internationally, offering visibility and opportunity to directly contribute to the companies' success. We realize that our strength and competitive advantage lie with our people. We support our employees in a number of ways to foster a healthy working environment, meaningful work, diversity and inclusion, mobility, networking and work-life balance. Our competitive compensation and benefit programs reflect Boehringer Ingelheim's high regard for our employees.

Duties & Responsibilities:

  • Develop and implement experimental ideas for delivering highly differentiated disease positioning concepts for targets in portfolio. Keep abreast of current literature and drive novel science by bringing new methods and assays relevant to Pulmonary Fibrosis-Interstitial Lung Diseases.
  • Ability to lead a group of scientists by directing and overseeing the design, execution and interpretation of studies.
  • As appropriate, serve as project Leader on portfolio projects. Responsible for working in collaboration with the Medicinal Chemistry or Biotherapeutics project leaders to shape and drive project strategy and advance the project up to start of clinical development.
  • Skilled in human cellular assay systems linked to fibrosis to establish strong NTC to disease linkage concepts using state of the art human disease ex vivo/in vitro models.
  • Collaborate with in vivo group to enable back translation of human disease-relevant mechanisms to in vivo models
  • Responsible for leading external collaborations and for establishing an external network to recruit and develop entry level Ph.D. and laboratory staff within the Disease positioning group.
  • Influence overall portfolio through engagement of departmental scientific reviews and providing strategic recommendations that will have impact on project direction and progression.
  • Develop scientific staff and mentor them in their experiments and for creating growth opportunities
  • Ensure compliance with all required training, safety, regulatory, HR, laboratory notebook, and intellectual property activities and corporate policies.

Sr. Principal Scientist Requirements:

  • Doctoral degree with at least 7 years drug discovery experience in pharmaceutical industry or biotech, or equivalent.
  • A proven track record of high research productivity in immunology and respiratory diseases. Deep understanding of mechanisms and pathways in respiratory diseases and current treatment modalities.
  • Ability to mentor Ph.D. scientists and lead a group of bench scientist(s) to deliver high quality data to contribute to overall program goals. Ability to proactive identification of critical issues and communicate effectively both orally and in writing in an inter-disciplinary environment.
  • The successful candidate will be an ambitious self-starter, be motivated to apply his/her skills to impact project needs and drive key innovative scientific concepts, and enjoy working in a fast-paced dynamic team environment and proven ability to focus and deliver high quality data that support timely decisions for projects.

Eligibility Requirements:

  • Must be legally authorized to work in the United States without restriction.
  • Must be willing to take a drug test and post-offer physical (if required)
  • Must be 18 years of age or older

Valid Through: 2019-9-13