Children's of Alabama is a pediatric acute care children's hospital located in Birmingham, Alabama. The main hospital has 332 beds and 48 bassinets. The hospital is affiliated with the University of Alabama at Birmingham School of Medicine. The hospital provides comprehensive pediatric specialties and subspecialties to pediatric patients aged 0–21 throughout Alabama and surrounding states. Children's of Alabama features the only level 1 pediatric trauma center in the state. The hospital was founded in 1911. The system's main hospital is located on the city's Southside, with additional outpatient facilities and primary care centers throughout central Alabama. It is the third largest children's hospital in the United States in terms of square footage.
The hospital is nationally ranked in multiple pediatric specialties.