Senior Scientist - Fusion Proteins Downstream Process Development


Trenton, NJ

Industry: Business Services


5 - 7 years

Posted 396 days ago

  by    Branden Lynch

Industry leader seeks an experienced Senior Scientist to design and develop downstream protein purification processes and perform process optimization of large molecule and recombinant proteins from traditional cell culture, microbial fermentation, or new and unconventional bioprocesses, including second generation therapeutic antibodies, antibody-drug conjugates, bi-specific antibodies, and fusion proteins. 




*** Lead technology and process transfer to internal or external manufacturers and proteins. 


*** Conduct downstream processes including: Conjugation, Centrifugation, Depth Filtration, Chromatography, Tangential Flow Filtration, and Viral Inactivation and Filtration. 


*** Set up scalable protein purification processes for various biologics candidates. Execute process scale up and transfer to Contract Manufacturing Organizations. 


*** Develop downstream platform processes such as harvesting, clarification, chromatography purification, and Ultrafiltration and Diafiltration.


*** Optimize high throughput screening methods and new technologies for process improvement. 


***Support discovery and preclinical development activities. 




*** PhD in Chemical Engineering, Biology, Chemistry, BiochemicalEngineering, or similar field. 


***4+ years of Industrial Protein Purification, Downstream Process Development, or similar experience for production of recombinant therapeutic proteins. 


*** Hands on knowledge of downstream process development, operations, process scale-up and technology transfer, and similar analytical methods. 


*** Knowledge of scale down model qualification and process optimization with risk analysis. 


Growth oriented and employee focused organization offers an industry competitive compensation package, bonuses, full medical benefits, 401(k) savings plan, tuition reimbursement, health and wellness benefits, generous paid vacation time, numerous professional development opportunities, and more! 

Please reference #37463283 when responding.Education Requirements: Doctorate degreeMinimum Experience Requirements: 5-10 yearsJob City Location: HamiltonJob State Location: NJJob Country Location: USASalary Range: $70,000 to $120,000

WE ARE AN EQUAL OPPORTUNITY EMPLOYER and our employment decisions are made without regard to race, color, religion, age, sex, national origin, handicap, disability or marital status. We reasonably accommodate individuals with handicaps, disabilities and bona fide religious beliefs. Jobs Career Position Hiring. CONSIDERED EXPERIENCE INCLUDES: Top 10 Job Site Top 10 Careers Site  Downstream Process Development Protein Purification Chromatography Tangential Flow Filtration Pharmaceuticals Biologics Therapeutics Scale Up Preclinical Development


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$70K - $120K