Discovery Sciences is a multi-faceted department which drives early drug discovery across AstraZeneca's global Research & Development portfolio. Mechanistic Biology & Profiling (part of Discovery Sciences), is a global, multidisciplinary department responsible for mechanism-of-action studies and compound profiling for efficacy and pre-clinical safety in support of the Oncology, Cardiovascular and Renal Disease, Respiratory, Inflammation & Autoimmunity, and Neuroscience portfolios.
If you're inspired by the possibilities of science to make a difference and ready to discover what you can do – join us.
Main Duties and Responsibilities
Reporting directly to the US Associate Director of the Mechanistic Biology & Profiling Department you will be an integral member of a team generating pre-clinical pharmacology data to predict and understand compound (and novel drug modalities) efficacy.
You will provide early, impactful mechanistic insight to projects across the Oncology and Neuroscience disease areas, through a combination of in vitro enzymology, pharmacology, and quantitative cell biology. You will be a skilled and passionate lab-based scientist, able to represent the department across a range of therapeutic projects and global initiatives, and also externally. You will drive scientific and technical innovation, including through external collaboration and partnership.