Senior Research Associate - Protein Purification & Characterization


Oregon, WI

5 - 7 years

Posted 214 days ago

  by    Branden Lynch

This job is no longer available.

Perform protein production through protein purification and biophysical characterization utilizing a broad spectrum of analytical lab instruments to support development of new kit and reagent products.


*** Design, execute, and analyze experiments.


*** Purify and characterize recombinant antibodies and related reagent proteins, spanning small scale discovery production through gram quantity productions supporting early development.


*** Execute large scale purification (>10L) of bioreactor productions.


*** Purify and characterize proteins using liquid chromatography (Affinity, Reverse Phase - High Performance Liquid Chromatography (RP-HPLC), Ion Exchange Chromatography (IEC), Size Exclusion Chromatography (SEC), Hydroxyapatite Chromatography (HC), and Hydrophobic Interaction Chromatography (HIC)), Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis (SDS - PAGE), Isoelectric focusing gels, and chemical conjugation.


*** Assist in antibody biophysical characterization using a wide range of techniques including differential scanning calorimetry (DSC), surface plasmon resonance (SPR), thermofluor, and similar.


***Support large scale protein production, purification, early buffer formation, and analytical characterization of antibodies.


*** Communicate results and analysis to project and group leaders and teams.


*** Serve as subject matter expert related to protein analytical analysis and characterization focusing on protein purification, chemical modification, analytical techniques, protein interaction analysis through SPR, and similar.


Dynamic organization offers an industry competitive compensation package, tuition reimbursement, bonuses, full medical benefits, 401(k) retirement plan, company laptop, cell phone, generous vacation time, numerous career development opportunities, and more!

Please reference #37929192 when responding.Education Requirements: Bachelor DegreeMinimum Experience Requirements: 5-10 yearsJob City Location: FitchburgJob State Location: WIJob Country Location: USA

$80K - $110K