Industry: Professional, Scientific & Technical Services•
8 - 10 years
Posted 62 days ago
Senior Director, Translational Science – AML In Bernards, NJ At DSI
Date Posted: 3/21/2019ApplyNot ready to Apply?Share With:
Senior Director, Translational Science – AML
Daiichi Sankyo Cancer Enterprise has a bold ambition to become a leading world- class organization in oncology based on 3 pillars: Antibody Drug Conjugates, AML and Breakthrough Science. To that end, we are looking for Translational Science leaders to help us quickly progress our new medicines from Discovery through clinical development and to registration.
The Cancer Enterprise AML franchise is pushing the boundaries of science aiming to define a new standard of care for patients with AML. Our AML pipeline currently has 5 compounds in the clinic across three mechanisms of action: Quizartinib (FLT3 inhibitor) in phase 3 development and Milademetan (DS-3032; MDM2 inhibitor), DS-3201 (dual inhibitor of EZH 1/2), PLX51107 and PLX2854 (BET / bromodomain and extra-terminal inhibitors) and DS-1001 (IDH1 inhibitor) in early clinical development.
This newly created position will be responsible for creating the strategy and will have programmatic responsibility for the Translational Science (TS) plan that will be incorporated into drug development programs of our key AML clinical assets within the Cancer Enterprise. The TS plan will include all aspects of pharmacodynamic and clinical biomarkers, companion diagnostics and nonclinical biology research needed to inform development decisions throughout the development life-cycle. The selected candidate will reportto the Global Head of Oncology Translational Development.
The candidate will work in collaboration with other members of global Daiichi Sankyo functional areas including preclinical research, biomarker research (BM/CDx/Ops),
CDx development, safety, clinical pharmacology, and global clinical development. The candidate will be a core member of the global program team and, depending on their potential and experience, lead the global translational sciences subteam.
Close interaction with global functions in Japan, US and Europe will be a key part of this job, as well as developing and maintaining strong collaborations and relations with external top scientists and physicians (including representing DS at key congresses and meetings).
This position is based in Basking Ridge, NJ; Travel expected to be ~ 30%
Experience and Required Skills
Daiichi Sankyo, Inc., is an equal opportunity/affirmative action employer. All qualified applicants will receive consideration for employment without regard to sex, gender identity, sexual orientation, race, color, religion, national origin, disability, protected veteran status, age, or any other characteristic protected by law.