Scientist / Sr Scientist

11 - 15 years experience  •  Biotech/Pharma

Salary depends on experience
Posted on 09/22/17
Waltham, MA
11 - 15 years experience
Salary depends on experience
Posted on 09/22/17

Position Description:

The Neurophysiology group within the Research and Development organization is searching for an experienced neurobiologist with a deep passion for understanding neural circuit functions in the normal and diseased brain.  Individuals with exceptional experience in in vivo electrophysiology are encouraged to apply.  The candidate is expected to perform extensive extracellular single- and multi-unit recordings in addition to electroencephalography (EEG) and event-related potential (ERP) recordings in freely behaving rodents to probe the neural circuit basis of psychiatric disorders and evaluate the effects of novel therapeutics and identify translational electrophysiological approaches to better predict the actions of novel therapeutics in clinical populations.

Key Duties:

  • Design, develop, and implement in vivo electrophysiological  protocols and assays
  • Engage in thorough analysis of data collected, generate summaries and interpretations of results, and present summaries within the Neurophysiology group, Biology Department, and the greater Alkermes community
  • Explore and apply new models, methodologies, and technologies to expand the group’s capabilities and help drive programs forward


Technical Skills:

  • Proficient in in vivo electrophysiological techniques in freely moving and anesthetized rodents (primarily rats) is required
  • Experience in in vitro electrophysiological techniques is beneficial
  • Proficient in EEG/LFP signal processing (i.e. FFT, Wavelet analyses), spike-train analysis and single unit isolation routines is required
  • Significant experience with rodent behavioral paradigms is highly desired
  • Solid background in in vivo pharmacology is highly desired
  • Experience with optogenetic/chemogenetic techniques in vivo is highly desired
  • Significant programming experience (i.e. Matlab, Python, etc…) is highly desired

Personal Skills:

  • Must work well in a team environment and have excellent intrapersonal skills
  • Well organized and able to multi-task
  • Outstanding personal initiative with the ability to take the lead, influence, and motivate others
  • Strong desire to push the boundaries of the science, champion innovative technologies and approaches, and be flexible to learn and take on new tasks when needed
  • Strong communication skills and ability to distill complex datasets into meaningful, actionable information

Minimum Education and Experience:

  • A Ph.D. in neuroscience, neurobiology, or related discipline with 3+ years of post-doc experience, or a MSdegree with 10+ years of equivalent experience, is required.
  • Experience in a biotechnology/pharmaceutical setting is strongly preferred but not required


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