Scientist - Sr

Quest Diagnostics   •  

San Juan Capistrano, CA

Industry: Healthcare


5 - 7 years

Posted 171 days ago

This job is no longer available.

Job Summary

Advanced Diagnostics-Genetics, Genomics and R&D currently has an established program where scientists and physician-scientists design, develop and validate diagnostics tests using state of the art technology including next generation sequencing. To accelerate growth and fulfill the development pipeline, the dedicated Test Design and Development Team (TdT) will consist of scientists, variant annotators and genetic professionals. Each TdT member will contribute his/her expertise in defining the molecular diagnostic test, both new and life cycle management tests, including its content, performance characteristics and requirements for test launch. Relevant scientific and clinical literature and variant databases will be investigated, supporting documents and launch materials will be developed, and reporting templates will be prepared by the TdT. The TdT will also help facilitate test structure build, eDBR process, user acceptance testing, and enhanced reporting.



Job Accountabilities

  1. Responsible for gathering medical genetic information on the different genes in a test panel to be developed and when relevant, competitive test information for use in the definition of the new test product.


  1. Integral team member of new test panel launches. Facilitate work between the R&D team and the Franchise to ensure clinical utility of test panel, appropriate test code structure, content of reporting template, canned comments for each gene in a disease group, eDBR document submissions, appropriate enhanced reports, and accurate communication and messaging with new products.


  1. As TdT member, investigate the clinical significance of gene variants, search internal datasets, online mutation databases, and published scientific and clinical literature or other academic resources


  1. Contribute to the development and preparation of white paper for the test panel.


  1. Help in the development of educational presentations to clients and payors and work with product director and Scientific Publications to develop literature for both MD professionals and patients for new tests, both written and online materials.


  1. May serve as consultant on the clinical utility and uses of specific tests and contribute to the development of test dossiers to support clinical utility of test offerings to insure payment by 3rd party payers.May work with IT to design, format and provide content for web-based portal with educational literature and videos for both patients and clients.


  1. Contributing to scientific literature through submission of abstracts, original articles, talks, posters etc. would be expected.  Collaborations with internal colleagues and with clients are strongly encouraged.


  1. Contributes ideas for new product development typically within existing markets.


  1. Works within established parameters on individual assignments, on project teams for longer-term projects or as a leader for a project team or group. Presents results/outputs to supervisor or project team members and contributes ideas to improve team processes.


  1. Perform additional related tasks as assigned.




Job Requirements


  1. Requires molecular biology and genetics knowledge and research skills acquired through the successful completion of a post-graduate degree. Ph.D. with thesis training in Genetics, Molecular Biology, or related scientific discipline. Ph.D. is preferred, but will take into consideration M.S. degree with at least 4 years of relevant experience.

  2. Ability to review and interpret peer-reviewed scientific journal articles.

  3. Proficiency in accessing online databases and other search engines.

  4. Solid understanding of sequencing and technologies with test design and development experiencepreferred.

  5. For annotator: ability to apply mathematical concepts to problem-solving situations. Demonstrate the ability to apply mathematical operations to such tasks as frequency distribution, analysis of variance and correlation techniques.

  6. Ability to apply common sense understanding to carry out instructions furnished in written, oral, or diagram form. Ability to deal with problems involving several variables in a variety of situations.

  7. Well-developed interpersonal skills and the ability to communicate with all levels of business, medical, and technical personnel.

  8. Excellent verbal and written communication skills.

  9. Exhibits scientific creativity and routinely demonstrates independent thought. 

  10. Possesses goal-oriented focus with comfort in a fast-paced environment.

  11. Ability to multi-task and prioritize responsibilities.

  12. Strong analytical skills and proficiency in using Office software such as Excel and Word. 

  13. Ability to work effectively with local and national Quest Diagnostics’ teams.

  14. Demonstrated leadership, decision-making and organizational skills.

  15. 25%+ travelrequired