Scientist - Preclinical Pharmacology for CRISPR Therapy R&D
5 - 7 years experience • Business Services
Industry leader seeks a Principal Scientist to execute In Vitro and In Vivo pharmacology studies to deliver CRISPR/Cas9 therapeutics.
*** Serve as Pharmacology expert to the drug discovery team. Support pharmacology, PK, and toxicology studies.
*** Design and execute in vivo and ex vivo experiments to assess the efficacy and mode of action of therapeutics.
*** Conduct ex vivo procedures and analysis such as DNA/RNA isolation, qPCR, and ELISA.
*** Set up and implement in vivo efficacy studies to develop CRISPR/Cas9 delivery platform.
*** Deliver DNA/RNA protein by lipid based transfection reagents.
*** Develop qualification protocols, standard operating procedures, and similar.
*** Masters degree in Chemistry, Pharmacology, Biochemistry, or similar.
*** 10+ years of experience developing and validating immunochemical, cell based assays, or similar.
*** Hands on knowledge of animal model development including animal handling, dosing, and surgery.
*** Experience with cell isolation and culturing, PCR, and similar molecular biology techniques.
Join a well funded and innovative organization offering an industry competitive compensation package, bonuses, full medical benefits, 401(k) retirement plan, life and disability insurance, career development opportunities, comprehensive vacation policy, and more!
Please reference #37432102 when responding.
Education Requirements: Doctorate degreeMinimum Experience Requirements: 5-10 yearsJob City Location: GlendaleJob State Location: CAJob Country Location: USASalary Range: $80,000 to $145,000
Diedre Moire Corporation, Inc.
WE ARE AN EQUAL OPPORTUNITY EMPLOYER and our employment decisions are made without regard to race, color, religion, age, sex, national origin, handicap, disability or marital status. We reasonably accommodate individuals with handicaps, disabilities and bona fide religious beliefs. Jobs Career Position Hiring. CONSIDERED EXPERIENCE INCLUDES:
Top 10 Job Site Top 10 Careers Site PK PD Pharmacokinetics Pharmacology Pharmaceuticals Translational Medicine QSP modeling Biomedical EngineeringDrug Discovery
DISCLAIMER: We will make every effort to consider applications for all available positions and shall use one or more of the contact methods and addresses indicated in resume or online application. Indicated location may be proximate or may be desirable point of embarkation for paid or unpaid relocation to another venue. Job descriptions may fit single or multiple presently available or anticipated positions and are NOT an offer of employment or contract implied or otherwise. Described compensation is not definite nor precise and may be estimated and approximate and is negotiable depending on market conditions and candidate availability and other factors and is solely at the discretion of employers. Linguistics used herein may use First Person Singular and First Person Plural grammatical person construction for and with the meaning of Third Person Singular and Third Person Plural references. We reserves the right to amend and change responsibilities to meet business and organizational needs as necessary. Response to a specific posting or advertisement may result in consideration for other opportunities and not necessarily the incentive or basis of the response. Nothing herein is or may be considered a promise, guarantee, offer, pledge, agreement, contract, or oath.