Scientist Pharmacology ( Non-Ph.D. )

Pfizer   •  

Cambridge, MA

Industry: Biotech/Pharma


5 - 7 years

Posted 292 days ago

This job is no longer available.

Job Focus

Highly motivated individual to work in a challenging environment within the preclinical pharmacology group. As part of this team, this person will be supporting in vivo studies and analyzing samples obtained from these studies. Responsible for conducting and managing in vivo studies to determine the efficacy of both small molecule and biotherapeutic approaches. The evaluation and development of new technologies, biomarkers and in vivo models are key components of this position.


  • Plan and conduct of in vivo studies in support of Inflammation & Immunology therapeutic portfolio
  • Formulation of compounds and administration of drugs and experimental compounds by various routes
  • Collection of blood and various tissues
  • Scoring of study animals
  • Ability to learn and conduct other animal-related techniques
  • Ex vivo analysis of animal samples
  • Maintaining well-organized records and documentation
  • Data entry and analysis


  • M.Sc. or B.Sc. degree in physiology, pharmacology, or related biological science
  • B.Sc. degree with 6+ years or M.Sc. degree with 5+ years’ experience
  • Experience working with small laboratory animals, preferably in a biotech or pharmaceutical environment
  • Well established hands-on experience with rodent in vivo dosing and handling techniques
  • Understanding of immunology or cell biology
  • Experience with animal models of autoimmunity and/or inflammation is desirable
  • Good organizational and communication skills, ability to focus attention to details
  • A high degree of flexibility, and a willingness and ability to work as a team member
  • Weekend work may be required

Technical expectations

  • Design and conduct experiments to support the mechanistic and disease biomarker discovery for in vivo models
  • Planning, coordination and execution of in vivo and ex vivo pharmacology studies in rodent models
  • Experience with small animal handling procedures, injections, oral dosing
  • Experience in tissue dissection and tissue preparation for histology, RNA, and protein analysis
  • Experience in molecular biology techniques such as ELISA, FACS, TLDA and RT-PCR, CBA and Luminex assays
  • Analyzing and presenting data to individuals and in group settings