$80K — $100K *
Essential Job Functions:
The contractor will act as a Tissue/Cell-Engineering expert at the Scientist II level to assist in projects dedicated to the study of complex in vitro cellular models (i.e. microphysiological systems, organ chips, spheroids/ organoids) and cells differentiated from induced pluripotent stem cells (iPSCs) that have high potential for predicting clinical effects of drugs in vitro.
The activities of the Scientist II are listed in the tasks below:
• Develop assigned research projects with defined deliverables related to regulatory critical needs in drug development.
• Work with supervisors, project leads and mentors to execute planned research projects.
• Performs experimental assignments defined in experimental and research plans, where deliverables and goals are well defined.
• Developing and validating protocols and standard operation procedures (SOPs) to assemble, maintain, use and assay complex in vitro cellular systems.
• Developing and validating approaches to perform quality control of complex in vitro cellular systems and mammalian cells, including iPSCs and iPSC-differentiated cells.
• Produces reports of reliable, comprehensive, and validated experiments with cells and cellular systems (prepares, edit, and designate project reports).
• Follows DARS established procedures to produces and document protocols, experimental plans, research plans, SOPs, results, data analysis, presentations, lab notebook, reports and manuscripts
• Revises existing SOPs and originates new documentation.
• Ensures that all work follows all pertinent Standard Operating Procedures, Good Laboratory Practice and safe work practices.
• Performs maintenance tasks to ensure cleanliness and proper operation of the DARS Integrated Cellular Systems Laboratory
• Mentors ORISE Fellows or Summer Fellows in performing established and planned tasks or assignments.
• Collaborates with other researchers in the lab and in other FDA labs or external labs.
• Actively prepares results and data to present in project meetings and participates in these meetings that occur every month.
• Actively participates in weekly group meetings.
Education Requirement: A Ph.D. in bioengineering, biomaterials, bio-microfluidics or equivalent
• Postdoctoral experience in complex in vitro cellular models
• At least four years of experience in research involving microdevices for culturing mammalian cells
• Hands-on laboratory experience in cell and molecular biology
• 1-4 years of work experience in research labs in academia or industry
Other Requirement(s): This position requires U.S. Citizenship or a Green Card holder and the ability to obtain and maintain a Government public trust level security clearance. For a candidate that is a Green Card holder, they must have lived in the United States for at least three out of the past five years prior to your application date. You will also meet the residency qualifications if you lived abroad while on government or military duty or if you were a dependent of a federal employee of military member.
• Experience in soft lithography and micromoulding
• Experience with in vitro drug testing and bioanalytics
• Experience in culturing and evaluating the function of hepatic or lung epithelial cells
• Skills in differentiating inducted pluripotent stem cells
Equipment Operated: Standard office equipment including computers, fax machines, copiers, printers, telephones, etc.
Work Environment: Work performed in an office environment. Involves frequent contact with staff and customers.
Mental/Physical Requirements: Manual dexterity for office machine operation; stooping, bending to handle files and supplies, mobility to complete errands or deliveries. Must be able to remain in stationary position for extended periods of time. Stress can be triggered by multiple demands and deadlines.
Valid through: 11/8/2021