Scientist I

Illumina   •  

San Diego, CA

Industry: Biotech/Pharma


Not Specified years

Posted 393 days ago

We are seeking an exceptionally talented, highly creative and self-motivated Scientist to join our dynamic interdisciplinary protein engineering group. Tasks will include designing and executing biophysical and biochemical assays for novel enzymatic processes, including DNA clustering in nano-patterned surfaces, to be used in Illumina’s Next Generation Sequencing (NGS) platforms. The successful candidate will have a strong interdisciplinary background in experimental biophysics and biochemistry. The candidate will be working collaboratively with multidisciplinary teams.

Preferred Educational Background:

  • PhD in biophysics, biochemistry, chemistry, or bioengineering with exceptional publication and proven graduate work record.

Preferred Experiential Background:

  • Broad experience with complex experimental design and assay development.
  • Interdisciplinary expertise in two or more of the following fields: protein biochemistry, molecular biology, experimental biophysics
  • Some familiarity with optics and instrumentation for fluorescence microscopy.
  • Strong expertise in data analysis and visualization skills
  • Demonstrated ability to quickly learn, adapt or adopt findings from other fields of science
  • Demonstrated ability to find unique and creative assay solutions to scientific problems
  • Demonstrated capability of high quality work and keen attention to detail.
  • Abilities to communicate effectively, work independently and collaboratively in a fast-paced team environment.

Optional Experiential Background that will distinguish the candidate from the norm:

  • Knowledge of  programming (Matlab, Python, C++, C# etc.) for complex data acquisition and analysis is a plus
  • Experience in expression, purification and biochemical characterization of at least one  nucleic acid interacting protein such as recombinase, polymerase, reverse transcriptase, helicase, SSB, chromatin remodeling enzyme, etc. is a plus
  • Knowledge and experience with enzyme kinetics and protein conjugation chemistry & techniques is a plus.
  • Experience with various single molecule techniques, such as fluorescence spectroscopy is a plus
  • Experience of surface polymer passivation is a plus
  • Experience with ultra-high resolution imaging techniques is a plus (STORM, STED etc.)
  • Sound understanding of the latest genomicstechnologies, methodologies, bioinformatics and NGS is a plus
  • 1+ years of postdoc or industry experience is a plus