At the Janssen Pharmaceutical Companies of Johnson& Johnson, we are working to create a world without disease. Transforming lives by finding new and better ways to prevent, intercept, treat and cure disease inspires us. We bring together the best minds and pursue the most promising science. Development, LLC is part of the Janssen Pharmaceutical Companies.
The Lead Discovery team is a critical part of the Discovery Sciences (DS) organization in Janssen R&D, and is committed to the delivery of high quality chemical leads needed for the generation of small molecule clinical compounds in all five Janssen Therapeutic Area (TA) discovery teams. This mission requires deep scientific expertise in a number of disciplines including chemistry, cellular and molecular pharmacology, enzymology, and screening technologies coupled with an ability to work collaboratively with internal and external partners. We are currently seeking an outstanding individual with chemical proteomics expertise to join our team. This position will be a part of the chemical biology/chemoproteomics team within the Molecular & Cellular Pharmacology Group, and will report to a senior member based in La Jolla, CA.
The candidate will be a key member of the Molecular & Cellular Pharmacology group, and provide proteomics support and biochemical expertise to therapeutic area programs from target nomination through declaration of a clinical candidate. The candidate will provide chemical biology and proteomics expertise to internal programs as well as external collaborations. S/he will contribute to establishment of robust workflow of LC-MS-based proteomics, maintenance of LC-MS platforms, and quantitative data analysis. The candidate will use quantitative proteomics to elucidate compound mechanism-of-action and carry out supporting biochemical and cellular validation. S/he will collaborate in a highly multidisciplinary/matrix environment for the progression of drug discovery projects.