In 2012, Berry founded Seres Therapeutics, which pioneered microbiome therapeutics. The company raised over $130M as a private company, including a $65M investment from Nestle Health Sciences. Seres publicly listed on the Nasdaq under the symbol MCRB in June 2015, raising $134M. Seres signed a partnership valued at $2B with Nestle Health Sciences in early 2016.
In 2014, Berry founded Indigo to create seed treatments that optimize the health of a plant to increase yield.
In 2009, Berry founded Axcella Health, which is pioneering defined a new approach to treating complex diseases and supporting health using Endogenous Metabolic Modulators as a new therapeutic product class.
In 2014, Berry founded Evelo Biosciences.
In 2007, Berry founded Joule Unlimited. In March 2010 and again in March 2011, Joule was named by Technology Review as one of the 50 Most Innovative Companies. Joule was named as one of the 10 most important emerging technologies in 2011.
Berry is a founding member of the Leadership Council of the United Nations Sustainable Development Solutions Network, which authored the Sustainable Development Goals. The Sustainable Development Goals contains 17 goals and 169 targets agreed to by 193 countries at the United Nations to foster sustainable development with a 2030 target.