$80K — $100K *
We are seeking experimental research scientists to join a new team at the Broad Institute to build a Human Gene Regulation Map.
This effort, led by Institute Director Eric Lander, will seek to understand the fundamental wiring of the noncoding genome and build a reference atlas for discovering biological mechanisms on common genetic diseases.
We are looking for highly motivated individuals to join this team to make fundamental discoveries in mapping regulatory DNA in various cell types and tissues, understanding cellular programs, and developing new tools to uncover mechanisms of disease. This team will develop and apply technologies combining CRISPR, single-cell measurements, and epigenomic tools in human cells and tissue to understand genetic regulation in health and disease.
The Lander Laboratory is a dynamic, innovative and interdisciplinary workplace and is seeking to hire an exceptional scientist who will work closely both the Lander Lab and collaborators throughout the Broad community in this next foundational project to understand the human genome.
· Lead and collaborate with scientists and research associates to make fundamental discoveries about gene regulation and disease genetics
· Develop and apply functional genomics techniques, including epigenomics, single-cell, transcriptomics, and CRISPR-based assays in human cells and tissues
· Work with the Lander Lab and the wider Broad community to integrate emerging technology and streamline data generation and analysis.
· Design and lead independent projects including developing methods, techniques and evaluation criteria for obtaining results
· Make significant contributions to scientific papers, quantitative data analyses and presentations
· Contribute to generation of protocols and data analyses
· Work with multidisciplinary team to achieve project goals
· Ph.D. in Molecular Biology, Biochemistry, Genetics or related life science field
· Additional 3+ years of relevant laboratory experience in academic or industry setting strongly preferred
· Strong hands-on experience in molecular biology, genomics, and cellular biology (cell-based assays, primary and cell line culture)
· Experience with genome editing tools including, CRISPR targeting in various human cell types including human ES/iPS cells or single-cell RNA-seq highly desirable
· Experience with quantitative data analysis. Proficiency in computational methods is a plus
· Proven track record of critical scientific thinking, multi-tasking ability, and strong analytical and problem-solving skills
· Excellent interpersonal and collaborative skills, and the ability to work both independently and as part of a team with scientists from a wide range of research expertise
· Outstanding verbal and written communication abilities
· Ability to adapt to and effectively manage changes in a fast paced and dynamic environment
Valid through: 2/16/2021