This Principal Scientist will contribute to the discovery of novel therapeutics within the Rare Diseases Drug Discovery Unit (RD DDU), independently designing pre-clinical scientific research projects. With a focus on rare hematological disorders (non-oncology), this scientist will also be a senior scientific consultant on multiple programs, and will lead matrixed teams to build our vision to discover therapeutics to transform the lives of patients worldwide.
- Design and direct research strategy and activities to meet program goals; provide leadership, timelines and contingency plans
- Establish project direction integrating science, essential technical knowledge, and program goals
- Work with other departments, being the scientific authority within discipline
- Be a senior company / project representative at external conferences, or business meetings
- Independently manage workload and expectations
- Identify project goals, activities and constraints and propose mitigation plans
- Communicate project status, risks and changes to plan to leadership team
- Guide a small team of internal scientists and help build their scientific and career development goals
- Contribute to the preparation/editing/review of documents for regulatory submission
- Be an essential liaison with external collaborators and team members and help guide research strategy in the focused therapeutic area
EDUCATION, BEHAVIOURAL COMPETENCIES AND SKILLS:
- PhD degree in a scientific discipline with 6+ years experience ,or MS with 12+ years experience , or BS with 14+ years experience in a biopharmaceutical R&D, health-related consulting company, or academic role focusing on preclinical research.
- You have passion for early drug discovery, along with the following attributes
- A background in hematological disorders, with experience in biologics and gene therapies
- An understanding of biological mechanisms that improve thrombosis and hemostasis, and preclinical models for studying these pathways
- Experience delivering novel therapeutics from idea to early clinical development.
- The ability to work cooperatively within a team setting is essential
- Demonstrate the capability to inspire and motivate others and build authentic relationships
- Demonstrate desire to participate in teams in a matrix organizational structure
- Experience in completion of project deliverables
- An in-depth understanding of clinical needs as it relates to guiding early programs towards successful translation to therapeutics to bring meaningful benefit to patients
- Manage across multiple projects
- Expected to lead matrix teams to meet project goals.
- Manage research vendors including negotiating sponsored research agreements/contracts, analyzing scope of work, facilitating the resolution of actions and issues.
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