Not Specified years
Posted 59 days ago
A Research Fellow at Mayo Clinic is a temporary position intended to provide training and education in research. Individuals will train in the research program of a Mayo Clinic principal investigator. Qualified individuals will demonstrate the potential for research as evidenced by their training and peer-reviewed publications and should become competitive for national research grants. Proof of English proficiency is required for J-1 Short-Term Scholars, Research Scholars, Professors, Specialists, and Student Interns sponsored by Mayo Clinic. Please attach the following required documents at the time of application.
Targeted chemotherapy delivery and capture. A new position in the field of bioengineering and translational interventional radiology research is available for a highly enthusiastic Postdoctoral Fellow to lead research under a new NIBIB NIH grant that was recently awarded to our team.
The candidate will focus on VX2 rabbit liver cancer model development, device testing and optimization and be a member of a multidisciplinary team that includes clinicians, engineers and scientists. Testing of clinically applicable intravenous catheter strategies are performed in large animal models with a strong emphasis on translation of novel preclinical catheter designs. Goal of the project is to test whether novel catheter-based device strategies could be used to extract undesired chemotherapy from the circulation to avoid drug toxicity. The expertise of the PI laboratory includes molecular biology, biochemistry, angiography, large animal models, bioengineering and the use of sophisticated clinical image-guided techniques including, 3T MRI, Force CT imaging, elastography, and C-arm fluoroscopy with digital subtraction capability.
In terms of training and career goals, the PI will work with candidates on individual career development plans that may include the training in advanced career skills such as grant writing for NIH and regulatory work with the Food and Drug Administration (FDA). Future career goals for the applicant (towards the end of a multi-year training period in the Oklu lab) may include a transition to independence as a new PI or the potential of partaking in scientifically related entrepreneurial activities (contingent upon successful achievement of academic milestones). Other roles of the candidate include but not limited to development of research ideas, projects and study protocols, participate in weekly research meetings to generate relevant and novel research ideas for grant applications, correspondence with the Institutional Animal Care & Use Committee & Institutional Review Board , submit applications for new research projects, renew application for existing and on-going studies, and terminate completed projects. Preparation and Presentation of Abstracts for Podium or Poster, write abstracts for submission to annual scientific meetings, present accepted abstracts as podium or poster during scientific meetings. Manuscript writing and submission to scientific journals, complete manuscripts and submit to peer-reviewed journals.
The PI (Dr. Oklu) focusses on Patient Inspired Engineering; problems encountered in the clinic motivates his research focus (ACS Nano 2017 PMID: 28524668; Science Transl Med 2016 PMID:27856795; ACS Nano 2015 PMID: 26305171). Dr. Oklu is a Professor and Chair of Vascular and Interventional Radiology at Mayo Clinic Arizona and the Director of NIH funded Minimally Invasive Therapeutics Laboratory. His collaborator (MPI) is Ali Khademhosseini PhD (Endowed Professor of Bioengineering at UCLA and Associate Director for California NanoSystems Institute (CNSI).
800146; J2WRTP Qualifications Must have a Ph.D., M.D., or equivalent doctoral degree in a field deemed relevant by the program. Doctoral degree in Bioengineering or Engineering highly preferred. Research Fellow is appropriate for individuals who have completed no more than one prior postdoctoral fellowship, at Mayo Clinic or elsewhere.