The Department of Cellular and Molecular Physiology of The Pennsylvania State University College of Medicine invites applications from outstanding Ph.D. and/or M.D. scientists for the Leonard (Jim) Jefferson Endowed Professorship. The Department has undergone a major expansion within the thriving new research environment of the Milton S. Hershey Medical Center, located in Hershey, Pennsylvania. Under leadership of the Chair, Dr. Donald Gill, the Department is building in the broad areas of cellular, molecular and integrative approaches toward translational research in physiology. The search is open to applicants in many research areas including those studying molecular mechanisms of cell signaling, structure and function of channels/transporters and related diseases, redox signaling and mitochondrial dysfunction, and changes in contractile and structural proteins in disease states. We are seeking an established investigator with an exceedingly strong record of research accomplishment and who will complement departmental research interests in cardiovascular, pulmonary and musculoskeletal diseases, metabolic disorders, aging and cancer. Particular consideration will be given to those undertaking novel approaches utilizing, for example, advanced imaging technology, and/or developing research within the new cryo-EM center in the College of Medicine. The Department enjoys strong interactions with the Heart and Vascular Institute, the Cancer Institute, the Institute for Personalized Medicine, and the NIH-supported Clinical and Translational Science Institute within the Penn State Hershey Medical Center. Applicants with established funded research programs or who have recently obtained funding to transition into independent research are preferred. Promising early stage investigators with strong records of research accomplishment who have yet to receive funding will also be considered. Competitive start-up packages, recently renovated laboratory space, and strong core facilities, together provide an outstanding research environment.