Process Development Scientist - Viral Bioconjugates
Develop and execute scale-up activities for Good Manufacturing Practice (GMP) compliant bioconjugation processes, including familiarization, optimization, and trial runs.
*** Outline and execute laboratory scale experiments in support of GMP bioconjugation projects.
*** Plan, develop, and optimize synthetic routes.
*** Execute and deliver bioorganic reactions.
*** Purify and characterize proteins and protein conjugates using applicable modern techniques such as High Performance Liquid Chromatography, Liquid Chromatography, Mass Spectrometry, Fast Protein Liquid Chromatography (affinity purification, size exclusion chromatography, hydrophobic interaction chromatography, etc.), Sodium Dodecyl Sulfate - Polyacrylamide Gel Electrophoresis, Ultra Violet-Visible Spectroscopy, and similar.
*** Conduct protein to protein and fluorescent probe bioconjugation cross linking.
*** Coordinate with Quality Assurance and Quality Control Management teams to author and approve Standard Operation Procedures, batch records, and relevant documents.
*** Serve as subject matter expert for queries regarding protein chemistry, protein handling, purification, and characterization related to biologics downstream processes including ultrafiltration & diafiltration and column chromatography methods.
Growth oriented organization offers an industry competitive compensation package, bonuses, full medical benefits, 401(k) retirement plans, life and disability insurance, professional growth opportunities, relocation assistance, and more!
Please reference #37463523 when responding.Education Requirements: Bachelor DegreeMinimum Experience Requirements: 2-5 yearsJob City Location: GaithersburgJob State Location: MDJob Country Location: USA