Principal Scientist, NMR - Metabolomics

5 - 7 years experience  •  Biotech/Pharma

Salary depends on experience
Posted on 02/19/18
Spring House, PA
5 - 7 years experience
Biotech/Pharma
Salary depends on experience
Posted on 02/19/18

We are seeking a motivated and productive analytical chemist or biochemist at the PhD level with a strong understanding of Nuclear Magnetic Resonance (NMR)-based metabolomics to work within a metabolomics group at our Spring House, PA site. 

The candidate will have experience designing studies and extensive knowledge and hands-on experience of NMR methods for analysis of biological samples and structural elucidation of small molecules.  Knowledge of univariate and multivariate analysis of the results is essential. Bioanalytical and/or metabolomics publications are required.  As the position involves multi-disciplinary efforts and external collaborations, good interpersonal skills are needed.

The Scientist will be responsible for:

  • Collaborating with Janssen therapeutic teams and/or external partners in designing, performing and interpreting metabolomics studies
  • Preparation of various biological samples for NMR analysis, optimization of conditions, processing data, analyzing data and writing reports, and communicating results in a team environment
  • Reviewing literature to support on-going discovery projects and submit new project proposals.
  • Maintaining electronic laboratory notebook
  • Publishing in high impact peer reviewed journals

Qualifications

  • A PhD in chemistry or a related discipline with at least 5 years of hands on laboratory experience is required
  • High impact publications are required
  • Ability to conduct research experiments, including trouble shooting with minimal supervision is required
  • Knowledge of NMR and related metabolomics software is required
  • Experience using 2D NMR techniques for structural elucidation of small molecules is required
  • Hands-on experience or familiarity with LC-MS metabolomics techniques is preferred
  • Familiarity with Bruker NMR spectrometers and software is required
  • Proficiency in data analysis of large data sets and writing reports is required
  • A good understanding of biochemistry and pathway analysis is required
  • Experience in drug discovery environment is preferred

Requisition ID: 6364171219

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