- Plans, and conducts laboratory research in the field of viral vaccines, and develops necessary technologies and protocols required for the work
- Prepares viral immunogen candidates by mammalian cell culture, and purifies candidates to high levels of homogeneity using state-of-the-art purification procedures.
- Optimizes and characterizes viral vaccine candidate immunogens by assessment of the binding of monoclonal and polyclonal antibodies with known reactivity.
- Analyzes serum and mucosal samples from animals and humans for immune responses and binding specificities.
- Works as a team member in assisting with studies related to structural, biochemical, and immunological responses to viral antigens and candidate viral vaccines.
- Executes non-human primate vaccination and challenge studies by coordinating sampling and procedures directly with animal facility as well as processing of biological specimens.
- Assists in the preparation of funding applications for the U.S. Army Medical Research and Materiel Command, and/or extramural resources including nonprofit organizations.
- Must be proficient in biochemical and biophysical techniques and up-to-date knowledge of relevant HIV-1 literature.
- Performs data analysis, prepares graphical representation of data, prepares manuscripts for publication in peer reviewed scientific journals, assists in the preparation of scientific reports for funded projects, presents research data at in-house meetings and at National and International scientific conferences.
- Serves as an in-house consultant and takes lead on scientific collaborations both within and outside the institution as it pertains to the mission of the US MHRP program in consultation with supervisors.
- Attends all training and safety classes conducted by WRAIR and HJF.
- Completes other projects and duties as assigned
Required Knowledge, Skills, and Abilities: Knowledge of complex scientific procedures and techniques; knowledge and practical experience in biophysical techniques, fundamental immunology and familiarity with infectious disease concepts, biochemistry and purification of proteins, knowledge of HPLC/FPLC purification systems and protocols. Experience with protein design and immunogen preparation, and immunization studies is highly desirable. The incumbent should have excellent communication skills including the ability to efficiently prepare research papers and grants. They should have a strong publication record as evidenced by first-author publications in the HIV-1 field encompassing immunogen characterization and animal immunization projects. They should have the ability to work in an independent capacity, be able to design experiments, troubleshoot technical procedures, and be capable of supervising junior staff.
Minimum Education/Training Requirements: Ph.D. in related scientific discipline
Minimum Experience: 0-2 years of related post-doctoral research experience